Macrosomia Rates in Women with Diet-Controlled Gestational Diabetes: A Retrospective Study

Background. Current data on the rates of macrosomia in women with gestational diabetes mellitus (GDM) are heterogenous. No study has specifically examined macrosomia rates in women with diet-controlled gestational diabetes. Aims. To compare the rates of macrosomia between mothers with diet-controlle...

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Main Authors: Fatima Vally, Jeffrey Presneill, Thomas Cade
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Journal of Pregnancy
Online Access:http://dx.doi.org/10.1155/2017/4935397
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author Fatima Vally
Jeffrey Presneill
Thomas Cade
author_facet Fatima Vally
Jeffrey Presneill
Thomas Cade
author_sort Fatima Vally
collection DOAJ
description Background. Current data on the rates of macrosomia in women with gestational diabetes mellitus (GDM) are heterogenous. No study has specifically examined macrosomia rates in women with diet-controlled gestational diabetes. Aims. To compare the rates of macrosomia between mothers with diet-controlled GDM to mothers without diabetes mellitus. Methods. A retrospective study in which all patients with diet-controlled GDM and singleton pregnancies in 2014 were considered for inclusion in the study. These cases were individually matched to mothers without GDM and without type 1 or 2 diabetes. Cases were matched to parity, age, and BMI. Controls were selected from the same year and as close as possible to the date of delivery of the case. Primary outcomes were macrosomia, defined by estimated fetal weight >90th centile and >95th centile (separately). Results. The estimated adjusted odds ratio for the presence of maternal GDM in the presence of EFW > 90th percentile (adjusted for maternal age, BMI, gravidity, parity, baby gender, and EGA) was 0.63 (95% CI 0.30–1.3; P=0.21). The estimated adjusted odds ratio for the association of maternal GDM and EFW > 95th percentile was 0.66 (95% CI 0.26–1.7; P=0.38). Conclusions. Our findings suggest that macrosomia is not increased in women with diet-controlled GDM. The study registration number is AQA 16/01.
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spelling doaj-art-b73f681a0c874692b850f2b4aa3dade82025-08-20T03:39:29ZengWileyJournal of Pregnancy2090-27272090-27352017-01-01201710.1155/2017/49353974935397Macrosomia Rates in Women with Diet-Controlled Gestational Diabetes: A Retrospective StudyFatima Vally0Jeffrey Presneill1Thomas Cade2Department of Maternal Fetal Medicine, Pregnancy Research Centre, Royal Women’s Hospital, 20 Flemington Road, Parkville, Melbourne, VIC, AustraliaThe Royal Melbourne Hospital, City Campus, 300 Grattan St, Melbourne, VIC, AustraliaDepartment of Maternal Fetal Medicine, Pregnancy Research Centre, Royal Women’s Hospital, 20 Flemington Road, Parkville, Melbourne, VIC, AustraliaBackground. Current data on the rates of macrosomia in women with gestational diabetes mellitus (GDM) are heterogenous. No study has specifically examined macrosomia rates in women with diet-controlled gestational diabetes. Aims. To compare the rates of macrosomia between mothers with diet-controlled GDM to mothers without diabetes mellitus. Methods. A retrospective study in which all patients with diet-controlled GDM and singleton pregnancies in 2014 were considered for inclusion in the study. These cases were individually matched to mothers without GDM and without type 1 or 2 diabetes. Cases were matched to parity, age, and BMI. Controls were selected from the same year and as close as possible to the date of delivery of the case. Primary outcomes were macrosomia, defined by estimated fetal weight >90th centile and >95th centile (separately). Results. The estimated adjusted odds ratio for the presence of maternal GDM in the presence of EFW > 90th percentile (adjusted for maternal age, BMI, gravidity, parity, baby gender, and EGA) was 0.63 (95% CI 0.30–1.3; P=0.21). The estimated adjusted odds ratio for the association of maternal GDM and EFW > 95th percentile was 0.66 (95% CI 0.26–1.7; P=0.38). Conclusions. Our findings suggest that macrosomia is not increased in women with diet-controlled GDM. The study registration number is AQA 16/01.http://dx.doi.org/10.1155/2017/4935397
spellingShingle Fatima Vally
Jeffrey Presneill
Thomas Cade
Macrosomia Rates in Women with Diet-Controlled Gestational Diabetes: A Retrospective Study
Journal of Pregnancy
title Macrosomia Rates in Women with Diet-Controlled Gestational Diabetes: A Retrospective Study
title_full Macrosomia Rates in Women with Diet-Controlled Gestational Diabetes: A Retrospective Study
title_fullStr Macrosomia Rates in Women with Diet-Controlled Gestational Diabetes: A Retrospective Study
title_full_unstemmed Macrosomia Rates in Women with Diet-Controlled Gestational Diabetes: A Retrospective Study
title_short Macrosomia Rates in Women with Diet-Controlled Gestational Diabetes: A Retrospective Study
title_sort macrosomia rates in women with diet controlled gestational diabetes a retrospective study
url http://dx.doi.org/10.1155/2017/4935397
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AT jeffreypresneill macrosomiaratesinwomenwithdietcontrolledgestationaldiabetesaretrospectivestudy
AT thomascade macrosomiaratesinwomenwithdietcontrolledgestationaldiabetesaretrospectivestudy