A catalog of numerical centrosome defects in epithelial ovarian cancers

A catalog of numerical centrosome defects in epithelial ovarian cancers

Abstract Centrosome amplification, the presence of more than two centrosomes in a cell is a common feature of most human cancer cell lines. However, little is known about centrosome numbers in human cancers and whether amplification or other numerical aberrations are frequently present. To address t...

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Main Authors: Jean‐Philippe Morretton, Anthony Simon, Aurélie Herbette, Jorge Barbazan, Carlos Pérez‐González, Camille Cosson, Bassirou Mboup, Aurélien Latouche, Tatiana Popova, Yann Kieffer, Anne‐Sophie Macé, Pierre Gestraud, Guillaume Bataillon, Véronique Becette, Didier Meseure, André Nicolas, Odette Mariani, Anne Vincent‐Salomon, Marc‐Henri Stern, Fatima Mechta‐Grigoriou, Sergio Roman Roman, Danijela Matic Vignjevic, Roman Rouzier, Xavier Sastre‐Garau, Oumou Goundiam, Renata Basto
Format: Article
Language:English
Published: Springer Nature 2022-09-01
Series:EMBO Molecular Medicine
Subjects:
centrosomes
ovarian cancers
centrosome number alterations
Online Access:https://doi.org/10.15252/emmm.202215670
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