The negative linear relationship between oxidative balance scores and constipation: a cross-sectional study from NHANES 2005–2010
BackgroundThis study aimed to investigate the relationship between oxidation balance score (OBS) and constipation.MethodsAll data was collected from the 2005–2010 cycles of the National health and nutrition examination survey (NHANES) database. The relationship between OBS and constipation was analy...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2024-11-01
|
| Series: | Frontiers in Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2024.1471343/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849221357413335040 |
|---|---|
| author | Liqian Xuan Yang Chen Chang Liu Yahui Dai |
| author_facet | Liqian Xuan Yang Chen Chang Liu Yahui Dai |
| author_sort | Liqian Xuan |
| collection | DOAJ |
| description | BackgroundThis study aimed to investigate the relationship between oxidation balance score (OBS) and constipation.MethodsAll data was collected from the 2005–2010 cycles of the National health and nutrition examination survey (NHANES) database. The relationship between OBS and constipation was analyzed by logistic regression, restricted cubic spline. Trend analysis was used to explore whether there is a linear relationship between OBS quartiles and constipation, while interaction analysis was conducted to determine whether other factors influence the relationship between OBS and constipation. Subgroup analysis was used to examine the relationship between the two in different subgroups. The three machine learning algorithms including Xgboost, Randomforest, and AdaBoost was used to analyze the important component of OBS in constipation.ResultsA total of 8,074 participants were involved. We found that there was a negative linear relationship between OBS and constipation. The relationship also existed after adjusting for all possible confounders. The trend test showed that the higher the OBS, the lower the likelihood of developing constipation (P for trend<0.05). The interaction analysis showed that marital status and diabetes interact with OBS on constipation. The receiver operating characteristic analysis indicated that OBS had a good prediction efficiency on constipation, especially in participants without diabetes and with the status of married or living with a partner. We also found that the body mass index and magnesium were important OBS components related to constipation.ConclusionOxidation balance score was negatively associated with the occurrence of constipation in adults. Moreover, body mass index and magnesium were important OBS components related to constipation. |
| format | Article |
| id | doaj-art-b737c68834294252acdff710091c524e |
| institution | Kabale University |
| issn | 2296-858X |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj-art-b737c68834294252acdff710091c524e2024-11-15T04:45:15ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2024-11-011110.3389/fmed.2024.14713431471343The negative linear relationship between oxidative balance scores and constipation: a cross-sectional study from NHANES 2005–2010Liqian Xuan0Yang Chen1Chang Liu2Yahui Dai3Digestive Endoscopy Center, Department of Gastroenterology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaDepartment of Emergency, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaDepartment of Gastroenterology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaDepartment of Orthopedics, Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaBackgroundThis study aimed to investigate the relationship between oxidation balance score (OBS) and constipation.MethodsAll data was collected from the 2005–2010 cycles of the National health and nutrition examination survey (NHANES) database. The relationship between OBS and constipation was analyzed by logistic regression, restricted cubic spline. Trend analysis was used to explore whether there is a linear relationship between OBS quartiles and constipation, while interaction analysis was conducted to determine whether other factors influence the relationship between OBS and constipation. Subgroup analysis was used to examine the relationship between the two in different subgroups. The three machine learning algorithms including Xgboost, Randomforest, and AdaBoost was used to analyze the important component of OBS in constipation.ResultsA total of 8,074 participants were involved. We found that there was a negative linear relationship between OBS and constipation. The relationship also existed after adjusting for all possible confounders. The trend test showed that the higher the OBS, the lower the likelihood of developing constipation (P for trend<0.05). The interaction analysis showed that marital status and diabetes interact with OBS on constipation. The receiver operating characteristic analysis indicated that OBS had a good prediction efficiency on constipation, especially in participants without diabetes and with the status of married or living with a partner. We also found that the body mass index and magnesium were important OBS components related to constipation.ConclusionOxidation balance score was negatively associated with the occurrence of constipation in adults. Moreover, body mass index and magnesium were important OBS components related to constipation.https://www.frontiersin.org/articles/10.3389/fmed.2024.1471343/fulloxidation balance scoreconstipationcross-sectional analysisNational Health and Nutrition Examination Surveydigestive health |
| spellingShingle | Liqian Xuan Yang Chen Chang Liu Yahui Dai The negative linear relationship between oxidative balance scores and constipation: a cross-sectional study from NHANES 2005–2010 Frontiers in Medicine oxidation balance score constipation cross-sectional analysis National Health and Nutrition Examination Survey digestive health |
| title | The negative linear relationship between oxidative balance scores and constipation: a cross-sectional study from NHANES 2005–2010 |
| title_full | The negative linear relationship between oxidative balance scores and constipation: a cross-sectional study from NHANES 2005–2010 |
| title_fullStr | The negative linear relationship between oxidative balance scores and constipation: a cross-sectional study from NHANES 2005–2010 |
| title_full_unstemmed | The negative linear relationship between oxidative balance scores and constipation: a cross-sectional study from NHANES 2005–2010 |
| title_short | The negative linear relationship between oxidative balance scores and constipation: a cross-sectional study from NHANES 2005–2010 |
| title_sort | negative linear relationship between oxidative balance scores and constipation a cross sectional study from nhanes 2005 2010 |
| topic | oxidation balance score constipation cross-sectional analysis National Health and Nutrition Examination Survey digestive health |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2024.1471343/full |
| work_keys_str_mv | AT liqianxuan thenegativelinearrelationshipbetweenoxidativebalancescoresandconstipationacrosssectionalstudyfromnhanes20052010 AT yangchen thenegativelinearrelationshipbetweenoxidativebalancescoresandconstipationacrosssectionalstudyfromnhanes20052010 AT changliu thenegativelinearrelationshipbetweenoxidativebalancescoresandconstipationacrosssectionalstudyfromnhanes20052010 AT yahuidai thenegativelinearrelationshipbetweenoxidativebalancescoresandconstipationacrosssectionalstudyfromnhanes20052010 AT liqianxuan negativelinearrelationshipbetweenoxidativebalancescoresandconstipationacrosssectionalstudyfromnhanes20052010 AT yangchen negativelinearrelationshipbetweenoxidativebalancescoresandconstipationacrosssectionalstudyfromnhanes20052010 AT changliu negativelinearrelationshipbetweenoxidativebalancescoresandconstipationacrosssectionalstudyfromnhanes20052010 AT yahuidai negativelinearrelationshipbetweenoxidativebalancescoresandconstipationacrosssectionalstudyfromnhanes20052010 |