Efficient protein depletion by genetically controlled deprotection of a dormant N‐degron
Abstract Methods that allow for the manipulation of genes or their products have been highly fruitful for biomedical research. Here, we describe a method that allows the control of protein abundance by a genetically encoded regulatory system. We developed a dormant N‐degron that can be attached to t...
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| Main Authors: | Christof Taxis, Gunter Stier, Roberta Spadaccini, Michael Knop |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2009-04-01
|
| Series: | Molecular Systems Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/msb.2009.25 |
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