Infection-adapted emergency hematopoiesis promotes visceral leishmaniasis.

Cells of the immune system are derived from hematopoietic stem cells (HSCs) residing in the bone marrow. HSCs become activated in response to stress, such as acute infections, which adapt the bone marrow output to the needs of the immune response. However, the impact of infection-adapted HSC activat...

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Bibliographic Details
Main Authors: Belma Melda Abidin, Akil Hammami, Simona Stäger, Krista M Heinonen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-08-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1006422&type=printable
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