Ultrasensitive Optical Chemosensor for Cu(II) Detection
Herein, the main objective of this research is to design and synthesize a novel optical chemosensor, 2,6-Bis(4-dimethylaminophenyl)-4-(dicyanomethylene)-cyclohexane-1,1-dicarbo-nitrile (BDC), for detection of one of the most significant metal ions Cu(II). This novel fluorescent chemosensor exhibits...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | International Journal of Analytical Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2019/7381046 |
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| author | Sayed M. Saleh Reham Ali Fahad Alminderej Ibrahim A. I. Ali |
| author_facet | Sayed M. Saleh Reham Ali Fahad Alminderej Ibrahim A. I. Ali |
| author_sort | Sayed M. Saleh |
| collection | DOAJ |
| description | Herein, the main objective of this research is to design and synthesize a novel optical chemosensor, 2,6-Bis(4-dimethylaminophenyl)-4-(dicyanomethylene)-cyclohexane-1,1-dicarbo-nitrile (BDC), for detection of one of the most significant metal ions Cu(II). This novel fluorescent chemosensor exhibits unique optical properties with large Stokes shift (about 170 nm) approximately. The fluorescence and UV–vis absorption performance among the BDC probe and Cu(II) ions were examined in 1:9 (v/v) methanol–HEPES buffer (pH = 7.2) solution. Also, BDC displays high selectivity for Cu(II) concerning other cations. Moreover, this probe provides high selectivity and sensitivity based on their fluorescence properties and recognition abilities within a detection limit of the Cu(II) contents (LOD 2.3 x 10−7 M). The suggested mechanism of BDC sensor is attributed to the chelation process with Cu(II), to establish a 1:1 metal-ligand ratio complex with a binding constant (Kbind = 7.16 x 104 M−1). The detection process is accompanied by quenching the main emission peak of the BDC at 571 nm. All the experimental data were collected to investigate the effects of several important parameters such as reversibility and the concentration limits. Besides, we study the interference of various metal ions on selectivity and detection capacity of this significant Cu (II) ion. This novel chemosensor shows ultrasensitive, fast tracing of Cu(II) in the physiological pH range (pH 7.2) and therefore may propose a novel promising method for the investigation of the biological functions of Cu(II) in living cells. |
| format | Article |
| id | doaj-art-b7014bca36844d2eaaf3d9c785a0c593 |
| institution | OA Journals |
| issn | 1687-8760 1687-8779 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Analytical Chemistry |
| spelling | doaj-art-b7014bca36844d2eaaf3d9c785a0c5932025-08-20T02:23:09ZengWileyInternational Journal of Analytical Chemistry1687-87601687-87792019-01-01201910.1155/2019/73810467381046Ultrasensitive Optical Chemosensor for Cu(II) DetectionSayed M. Saleh0Reham Ali1Fahad Alminderej2Ibrahim A. I. Ali3Chemistry Department, Science College, Qassim University, Buraidah, Saudi ArabiaChemistry Department, Science College, Qassim University, Buraidah, Saudi ArabiaChemistry Department, Science College, Qassim University, Buraidah, Saudi ArabiaChemistry Department, Science College, Suez Canal University, Ismailia, EgyptHerein, the main objective of this research is to design and synthesize a novel optical chemosensor, 2,6-Bis(4-dimethylaminophenyl)-4-(dicyanomethylene)-cyclohexane-1,1-dicarbo-nitrile (BDC), for detection of one of the most significant metal ions Cu(II). This novel fluorescent chemosensor exhibits unique optical properties with large Stokes shift (about 170 nm) approximately. The fluorescence and UV–vis absorption performance among the BDC probe and Cu(II) ions were examined in 1:9 (v/v) methanol–HEPES buffer (pH = 7.2) solution. Also, BDC displays high selectivity for Cu(II) concerning other cations. Moreover, this probe provides high selectivity and sensitivity based on their fluorescence properties and recognition abilities within a detection limit of the Cu(II) contents (LOD 2.3 x 10−7 M). The suggested mechanism of BDC sensor is attributed to the chelation process with Cu(II), to establish a 1:1 metal-ligand ratio complex with a binding constant (Kbind = 7.16 x 104 M−1). The detection process is accompanied by quenching the main emission peak of the BDC at 571 nm. All the experimental data were collected to investigate the effects of several important parameters such as reversibility and the concentration limits. Besides, we study the interference of various metal ions on selectivity and detection capacity of this significant Cu (II) ion. This novel chemosensor shows ultrasensitive, fast tracing of Cu(II) in the physiological pH range (pH 7.2) and therefore may propose a novel promising method for the investigation of the biological functions of Cu(II) in living cells.http://dx.doi.org/10.1155/2019/7381046 |
| spellingShingle | Sayed M. Saleh Reham Ali Fahad Alminderej Ibrahim A. I. Ali Ultrasensitive Optical Chemosensor for Cu(II) Detection International Journal of Analytical Chemistry |
| title | Ultrasensitive Optical Chemosensor for Cu(II) Detection |
| title_full | Ultrasensitive Optical Chemosensor for Cu(II) Detection |
| title_fullStr | Ultrasensitive Optical Chemosensor for Cu(II) Detection |
| title_full_unstemmed | Ultrasensitive Optical Chemosensor for Cu(II) Detection |
| title_short | Ultrasensitive Optical Chemosensor for Cu(II) Detection |
| title_sort | ultrasensitive optical chemosensor for cu ii detection |
| url | http://dx.doi.org/10.1155/2019/7381046 |
| work_keys_str_mv | AT sayedmsaleh ultrasensitiveopticalchemosensorforcuiidetection AT rehamali ultrasensitiveopticalchemosensorforcuiidetection AT fahadalminderej ultrasensitiveopticalchemosensorforcuiidetection AT ibrahimaiali ultrasensitiveopticalchemosensorforcuiidetection |