Hyaluronic acid/silk fibroin nanoparticles loaded with methotrexate for topical treatment of psoriasis
Systemic administration of methotrexate (MTX), widely regarded as one of the most effective treatments for psoriasis, poses significant challenges due to its high toxicity, limited solubility, and potential for adverse effects. Consequently, developing a topical form of MTX may offer a safer and mor...
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| Main Authors: | Lan Cheng, Yanhua Zhang, Qian Xu, Zheng Li, Zulan Liu, Fangyin Dai |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-06-01
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| Series: | International Journal of Pharmaceutics: X |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590156724000847 |
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