Screening for Mild Cognitive Impairment in Parkinson’s Disease: Comparison of the Italian Versions of Three Neuropsychological Tests
Mild cognitive impairment (MCI) is frequent in Parkinson’s disease (PD). Recently proposed criteria for MCI in PD (PD-MCI) indicate level I diagnosis based on abbreviated assessment and level II based on comprehensive neuropsychological evaluation. The study explored the sensitivity and specificity...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Parkinson's Disease |
| Online Access: | http://dx.doi.org/10.1155/2015/681976 |
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| author | Angela Federico Alice Maier Greta Vianello Daniela Mapelli Michela Trentin Giampietro Zanette Alessandro Picelli Marialuisa Gandolfi Stefano Tamburin |
| author_facet | Angela Federico Alice Maier Greta Vianello Daniela Mapelli Michela Trentin Giampietro Zanette Alessandro Picelli Marialuisa Gandolfi Stefano Tamburin |
| author_sort | Angela Federico |
| collection | DOAJ |
| description | Mild cognitive impairment (MCI) is frequent in Parkinson’s disease (PD). Recently proposed criteria for MCI in PD (PD-MCI) indicate level I diagnosis based on abbreviated assessment and level II based on comprehensive neuropsychological evaluation. The study explored the sensitivity and specificity of the Italian versions of three neuropsychological tests for level I diagnosis of PD-MCI. We recruited 100 consecutive PD patients. After screening for inclusion criteria, 43 patients were included. The sensitivity and specificity of the Mini Mental State Examination (MMSE), the Montreal Cognitive Assessment (MoCA), and the Addenbrooke’s Cognitive Examination Revised (ACE-R) in comparison to level II diagnosis of PD-MCI were examined. PD-MCI was diagnosed (level II) in 51% of patients. Disease duration was significantly longer and PD motor scales were more severely impaired in MCI group. The receiver-operator characteristics curve documented nonsignificant difference in the performance of the three tests, with slight advantage of MMSE (corrected data). The time of administration favored MMSE. In Italian-speaking PD patients, MMSE might represent a good screening tool for PD-MCI, because of the shorter time of administration and the performance comparable to those of MoCA and ACE-R. Further studies are needed to validate the new PD-MCI criteria across different languages and cultures. |
| format | Article |
| id | doaj-art-b6f8cf92589e42ef95b32b4ecfc8f197 |
| institution | OA Journals |
| issn | 2090-8083 2042-0080 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Parkinson's Disease |
| spelling | doaj-art-b6f8cf92589e42ef95b32b4ecfc8f1972025-08-20T02:23:09ZengWileyParkinson's Disease2090-80832042-00802015-01-01201510.1155/2015/681976681976Screening for Mild Cognitive Impairment in Parkinson’s Disease: Comparison of the Italian Versions of Three Neuropsychological TestsAngela Federico0Alice Maier1Greta Vianello2Daniela Mapelli3Michela Trentin4Giampietro Zanette5Alessandro Picelli6Marialuisa Gandolfi7Stefano Tamburin8Department of Neurological and Movement Sciences, University of Verona, Piazzale Scuro 10, 37134 Verona, ItalyDepartment of Neurological and Movement Sciences, University of Verona, Piazzale Scuro 10, 37134 Verona, ItalyDepartment of General Psychology, University of Padova, Via Venezia 8, 35100 Padua, ItalyDepartment of General Psychology, University of Padova, Via Venezia 8, 35100 Padua, ItalyNeurology Unit Pederzoli Hospital, Via Monte Baldo 24, 37019 Peschiera del Garda, ItalyNeurology Unit Pederzoli Hospital, Via Monte Baldo 24, 37019 Peschiera del Garda, ItalyDepartment of Neurological and Movement Sciences, University of Verona, Piazzale Scuro 10, 37134 Verona, ItalyDepartment of Neurological and Movement Sciences, University of Verona, Piazzale Scuro 10, 37134 Verona, ItalyDepartment of Neurological and Movement Sciences, University of Verona, Piazzale Scuro 10, 37134 Verona, ItalyMild cognitive impairment (MCI) is frequent in Parkinson’s disease (PD). Recently proposed criteria for MCI in PD (PD-MCI) indicate level I diagnosis based on abbreviated assessment and level II based on comprehensive neuropsychological evaluation. The study explored the sensitivity and specificity of the Italian versions of three neuropsychological tests for level I diagnosis of PD-MCI. We recruited 100 consecutive PD patients. After screening for inclusion criteria, 43 patients were included. The sensitivity and specificity of the Mini Mental State Examination (MMSE), the Montreal Cognitive Assessment (MoCA), and the Addenbrooke’s Cognitive Examination Revised (ACE-R) in comparison to level II diagnosis of PD-MCI were examined. PD-MCI was diagnosed (level II) in 51% of patients. Disease duration was significantly longer and PD motor scales were more severely impaired in MCI group. The receiver-operator characteristics curve documented nonsignificant difference in the performance of the three tests, with slight advantage of MMSE (corrected data). The time of administration favored MMSE. In Italian-speaking PD patients, MMSE might represent a good screening tool for PD-MCI, because of the shorter time of administration and the performance comparable to those of MoCA and ACE-R. Further studies are needed to validate the new PD-MCI criteria across different languages and cultures.http://dx.doi.org/10.1155/2015/681976 |
| spellingShingle | Angela Federico Alice Maier Greta Vianello Daniela Mapelli Michela Trentin Giampietro Zanette Alessandro Picelli Marialuisa Gandolfi Stefano Tamburin Screening for Mild Cognitive Impairment in Parkinson’s Disease: Comparison of the Italian Versions of Three Neuropsychological Tests Parkinson's Disease |
| title | Screening for Mild Cognitive Impairment in Parkinson’s Disease: Comparison of the Italian Versions of Three Neuropsychological Tests |
| title_full | Screening for Mild Cognitive Impairment in Parkinson’s Disease: Comparison of the Italian Versions of Three Neuropsychological Tests |
| title_fullStr | Screening for Mild Cognitive Impairment in Parkinson’s Disease: Comparison of the Italian Versions of Three Neuropsychological Tests |
| title_full_unstemmed | Screening for Mild Cognitive Impairment in Parkinson’s Disease: Comparison of the Italian Versions of Three Neuropsychological Tests |
| title_short | Screening for Mild Cognitive Impairment in Parkinson’s Disease: Comparison of the Italian Versions of Three Neuropsychological Tests |
| title_sort | screening for mild cognitive impairment in parkinson s disease comparison of the italian versions of three neuropsychological tests |
| url | http://dx.doi.org/10.1155/2015/681976 |
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