Verteporfin Inhibits Severe Fever with Thrombocytopenia Syndrome Virus Infection via Inducing the Degradation of the Viral Gn Protein

Verteporfin Inhibits Severe Fever with Thrombocytopenia Syndrome Virus Infection via Inducing the Degradation of the Viral Gn Protein

<b>Background:</b> Severe fever with thrombocytopenia syndrome virus (SFTSV) is a novel tick-borne bunyavirus, causing the hemorrhagic infectious disease of SFTS, with a case fatality rate up to 30% due to the absence of effective therapeutic interventions. Therefore, it is urgent to dev...

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Bibliographic Details
Main Authors: Bingan Wu, Chenyang Yu, Yuxiang Lin, Ping Zhao, Zhongtian Qi, Xijing Qian
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Pharmaceutics
Subjects:
severe fever with thrombocytopenia syndrome virus
antiviral agents
verteporfin
viral binding
Gn protein
Online Access:https://www.mdpi.com/1999-4923/17/4/434
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