Transient Hypothyroidism in Premature Infants After Short-term Topical Iodine Exposure: An Avoidable Risk?
Studies in preterm infants have shown that prolonged treatment with topical iodine (multiple doses, often over multiple days) can transiently suppress thyroid function. However, it is uncertain if topical iodine exposure for very short periods of time can cause significant changes in thyroid functio...
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| Format: | Article |
| Language: | English |
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Elsevier
2013-04-01
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| Series: | Pediatrics and Neonatology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1875957212001660 |
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| author | Jordan E. Pinsker Krista McBayne Mary Edwards Kirk Jensen David F. Crudo Andrew J. Bauer |
| author_facet | Jordan E. Pinsker Krista McBayne Mary Edwards Kirk Jensen David F. Crudo Andrew J. Bauer |
| author_sort | Jordan E. Pinsker |
| collection | DOAJ |
| description | Studies in preterm infants have shown that prolonged treatment with topical iodine (multiple doses, often over multiple days) can transiently suppress thyroid function. However, it is uncertain if topical iodine exposure for very short periods of time can cause significant changes in thyroid function. We report two cases of transient hypothyroidism in preterm infants after short-term exposure to topical iodine during surgical preparation, and review their clinical and laboratory findings before and after iodine exposure. We conclude that premature infants are at risk of developing transient hypothyroidism in response to a single, short-term exposure to topical iodine, even in iodine-sufficient geographical areas. We advise monitoring of thyroid function in these infants after iodine exposure, as treatment with levothyroxine may be needed for a limited duration to prevent the sequelae of untreated hypothyroidism. Consideration of using alternative cleansing agents is also advised. |
| format | Article |
| id | doaj-art-b6ee10b59fe74a3a8f2bdd6376422cc9 |
| institution | Kabale University |
| issn | 1875-9572 |
| language | English |
| publishDate | 2013-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Pediatrics and Neonatology |
| spelling | doaj-art-b6ee10b59fe74a3a8f2bdd6376422cc92025-08-20T03:51:59ZengElsevierPediatrics and Neonatology1875-95722013-04-0154212813110.1016/j.pedneo.2012.10.005Transient Hypothyroidism in Premature Infants After Short-term Topical Iodine Exposure: An Avoidable Risk?Jordan E. Pinsker0Krista McBayne1Mary Edwards2Kirk Jensen3David F. Crudo4Andrew J. Bauer5Department of Pediatrics, Tripler Army Medical Center, Honolulu, HI, USADepartment of Pediatrics, Tripler Army Medical Center, Honolulu, HI, USADepartment of Surgery, Tripler Army Medical Center, Honolulu, HI, USADepartment of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USADepartment of Pediatrics, Wake Forest University, School of Medicine, Winston-Salem, NC, USADepartment of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USAStudies in preterm infants have shown that prolonged treatment with topical iodine (multiple doses, often over multiple days) can transiently suppress thyroid function. However, it is uncertain if topical iodine exposure for very short periods of time can cause significant changes in thyroid function. We report two cases of transient hypothyroidism in preterm infants after short-term exposure to topical iodine during surgical preparation, and review their clinical and laboratory findings before and after iodine exposure. We conclude that premature infants are at risk of developing transient hypothyroidism in response to a single, short-term exposure to topical iodine, even in iodine-sufficient geographical areas. We advise monitoring of thyroid function in these infants after iodine exposure, as treatment with levothyroxine may be needed for a limited duration to prevent the sequelae of untreated hypothyroidism. Consideration of using alternative cleansing agents is also advised.http://www.sciencedirect.com/science/article/pii/S1875957212001660hypothyroidismiodineinfant |
| spellingShingle | Jordan E. Pinsker Krista McBayne Mary Edwards Kirk Jensen David F. Crudo Andrew J. Bauer Transient Hypothyroidism in Premature Infants After Short-term Topical Iodine Exposure: An Avoidable Risk? Pediatrics and Neonatology hypothyroidism iodine infant |
| title | Transient Hypothyroidism in Premature Infants After Short-term Topical Iodine Exposure: An Avoidable Risk? |
| title_full | Transient Hypothyroidism in Premature Infants After Short-term Topical Iodine Exposure: An Avoidable Risk? |
| title_fullStr | Transient Hypothyroidism in Premature Infants After Short-term Topical Iodine Exposure: An Avoidable Risk? |
| title_full_unstemmed | Transient Hypothyroidism in Premature Infants After Short-term Topical Iodine Exposure: An Avoidable Risk? |
| title_short | Transient Hypothyroidism in Premature Infants After Short-term Topical Iodine Exposure: An Avoidable Risk? |
| title_sort | transient hypothyroidism in premature infants after short term topical iodine exposure an avoidable risk |
| topic | hypothyroidism iodine infant |
| url | http://www.sciencedirect.com/science/article/pii/S1875957212001660 |
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