SUMOylation-related genes define prognostic subtypes in stomach adenocarcinoma: integrating single-cell analysis and machine learning analyses

SUMOylation-related genes define prognostic subtypes in stomach adenocarcinoma: integrating single-cell analysis and machine learning analyses

BackgroundStomach adenocarcinoma (STAD) exhibits high molecular heterogeneity and poor prognosis, necessitating robust biomarkers for risk stratification. While SUMOylation, a post-translational modification, regulates tumor progression, its prognostic and immunological roles in STAD remain underexp...

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Bibliographic Details
Main Authors: Kaiping Luo, Donghui Xing, Xiang He, Yixin Zhai, Yanan Jiang, Hongjie Zhan, Zhigang Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
stomach adenocarcinoma
sumoylation
machine learning
L3MBTL2
VHL
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1527233/full
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