Fibroblast activation protein and the tumour microenvironment: challenges and therapeutic opportunities
Fibroblast Activation Protein (FAP) has emerged as a critical player in cancer biology, particularly in shaping the tumour microenvironment (TME) and influencing immunotherapy outcomes. FAP-positive cancer-associated fibroblasts (CAFs) play multiple roles in tumour progression and immune modulation....
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| Main Authors: | Hsing Hwa Lee, Zeyad Al-Ogaili |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-07-01
|
| Series: | Oncology Reviews |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/or.2025.1617487/full |
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