Directionality between cognitive function and daily physical activity patterns
Abstract INTRODUCTION Physical activity is a modifiable risk factor for dementia, but cognitive function is also important for physical activity engagement. This study evaluated the directionality of associations between daily physical activity and cognitive function in a sample of cognitively and p...
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| Format: | Article |
| Language: | English |
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Wiley
2025-04-01
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| Series: | Alzheimer’s & Dementia: Translational Research & Clinical Interventions |
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| Online Access: | https://doi.org/10.1002/trc2.70068 |
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| author | Francesca R. Marino Jennifer A. Deal Alden L. Gross Yang An Qu Tian Eleanor M. Simonsick Luigi Ferrucci Susan M. Resnick Jennifer A. Schrack Amal A. Wanigatunga |
| author_facet | Francesca R. Marino Jennifer A. Deal Alden L. Gross Yang An Qu Tian Eleanor M. Simonsick Luigi Ferrucci Susan M. Resnick Jennifer A. Schrack Amal A. Wanigatunga |
| author_sort | Francesca R. Marino |
| collection | DOAJ |
| description | Abstract INTRODUCTION Physical activity is a modifiable risk factor for dementia, but cognitive function is also important for physical activity engagement. This study evaluated the directionality of associations between daily physical activity and cognitive function in a sample of cognitively and physically intact older adults. METHODS Cognitive factor scores for domains including global cognition, memory, language, executive function/attention, and visuospatial processing, and physical activity patterns from wrist accelerometry were measured at two visits (mean: 1.8 years) among 237 cognitively intact older adults in the Baltimore Longitudinal Study of Aging (BLSA) (mean age: 76.5 years). Bivariate latent change score models estimated directionality of associations between changes in cognitive factor scores and physical activity patterns. Models were adjusted for age, sex, race, education, comorbidities, and body mass index. RESULTS Higher total amount of activity, longer activity bouts, less sedentary time, and less activity fragmentation at baseline were associated with less annual cognitive decline across multiple cognitive domains (X2 > 4.11, 1 df for all). In contrast, baseline cognitive factor scores were not associated with changes in any activity pattern (X2 < 3.20, 1 df for all). DISCUSSION Increasing movement and/or decreasing sedentary behavior is associated with less prospective cognitive decline. Targeting reductions in sedentary time and lengthening activity bouts may slow cognitive decline among older adults at risk for dementia. Highlights Greater activity engagement is related to less annual cognitive decline. Baseline cognition is not associated with short‐term changes in activity patterns. Promoting daily movement and lowering sedentary time may have cognitive benefits. |
| format | Article |
| id | doaj-art-b6cec97617d6427cbf4d120b33299d91 |
| institution | Kabale University |
| issn | 2352-8737 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | Alzheimer’s & Dementia: Translational Research & Clinical Interventions |
| spelling | doaj-art-b6cec97617d6427cbf4d120b33299d912025-08-20T03:30:02ZengWileyAlzheimer’s & Dementia: Translational Research & Clinical Interventions2352-87372025-04-01112n/an/a10.1002/trc2.70068Directionality between cognitive function and daily physical activity patternsFrancesca R. Marino0Jennifer A. Deal1Alden L. Gross2Yang An3Qu Tian4Eleanor M. Simonsick5Luigi Ferrucci6Susan M. Resnick7Jennifer A. Schrack8Amal A. Wanigatunga9Department of Anatomy & Neurobiology Boston University Chobanian & Avedisian School of Medicine Boston Massachusetts USADepartment of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore Maryland USADepartment of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore Maryland USAIntramural Research Program National Institute on Aging Baltimore Maryland USAIntramural Research Program National Institute on Aging Baltimore Maryland USAIntramural Research Program National Institute on Aging Baltimore Maryland USAIntramural Research Program National Institute on Aging Baltimore Maryland USAIntramural Research Program National Institute on Aging Baltimore Maryland USADepartment of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore Maryland USADepartment of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore Maryland USAAbstract INTRODUCTION Physical activity is a modifiable risk factor for dementia, but cognitive function is also important for physical activity engagement. This study evaluated the directionality of associations between daily physical activity and cognitive function in a sample of cognitively and physically intact older adults. METHODS Cognitive factor scores for domains including global cognition, memory, language, executive function/attention, and visuospatial processing, and physical activity patterns from wrist accelerometry were measured at two visits (mean: 1.8 years) among 237 cognitively intact older adults in the Baltimore Longitudinal Study of Aging (BLSA) (mean age: 76.5 years). Bivariate latent change score models estimated directionality of associations between changes in cognitive factor scores and physical activity patterns. Models were adjusted for age, sex, race, education, comorbidities, and body mass index. RESULTS Higher total amount of activity, longer activity bouts, less sedentary time, and less activity fragmentation at baseline were associated with less annual cognitive decline across multiple cognitive domains (X2 > 4.11, 1 df for all). In contrast, baseline cognitive factor scores were not associated with changes in any activity pattern (X2 < 3.20, 1 df for all). DISCUSSION Increasing movement and/or decreasing sedentary behavior is associated with less prospective cognitive decline. Targeting reductions in sedentary time and lengthening activity bouts may slow cognitive decline among older adults at risk for dementia. Highlights Greater activity engagement is related to less annual cognitive decline. Baseline cognition is not associated with short‐term changes in activity patterns. Promoting daily movement and lowering sedentary time may have cognitive benefits.https://doi.org/10.1002/trc2.70068accelerometrycognitive declinedementiaphysical activityprevention |
| spellingShingle | Francesca R. Marino Jennifer A. Deal Alden L. Gross Yang An Qu Tian Eleanor M. Simonsick Luigi Ferrucci Susan M. Resnick Jennifer A. Schrack Amal A. Wanigatunga Directionality between cognitive function and daily physical activity patterns Alzheimer’s & Dementia: Translational Research & Clinical Interventions accelerometry cognitive decline dementia physical activity prevention |
| title | Directionality between cognitive function and daily physical activity patterns |
| title_full | Directionality between cognitive function and daily physical activity patterns |
| title_fullStr | Directionality between cognitive function and daily physical activity patterns |
| title_full_unstemmed | Directionality between cognitive function and daily physical activity patterns |
| title_short | Directionality between cognitive function and daily physical activity patterns |
| title_sort | directionality between cognitive function and daily physical activity patterns |
| topic | accelerometry cognitive decline dementia physical activity prevention |
| url | https://doi.org/10.1002/trc2.70068 |
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