Colonic Malakoplakia in a Liver Transplant Recipient
Malakoplakia is a rare inflammatory condition seen in transplant patients. There are two previously reported cases of malakoplakia involving the gastrointestinal tract in liver transplant patients. The present paper reports a case of colonic malakoplakia in a 58-year-old woman, a liver transplant re...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2007-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/2007/256031 |
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| _version_ | 1850160293810798592 |
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| author | Peter TW Kim Jennifer E Davis Siegfried R Erb Eric M Yoshida Urs P Steinbrecher |
| author_facet | Peter TW Kim Jennifer E Davis Siegfried R Erb Eric M Yoshida Urs P Steinbrecher |
| author_sort | Peter TW Kim |
| collection | DOAJ |
| description | Malakoplakia is a rare inflammatory condition seen in transplant patients. There are two previously reported cases of malakoplakia involving the gastrointestinal tract in liver transplant patients. The present paper reports a case of colonic malakoplakia in a 58-year-old woman, a liver transplant recipient who was receiving immunosuppressive drugs. She presented with chronic diarrhea while on tacrolimus. There was no history of antecedent infection. Colonoscopy showed patchy mucosal edema, but no discrete yellow plaques or nodules. The diagnosis was made by colon biopsies, which showed chronic inflammation with many histiocytes containing Michaelis-Gutmann bodies. Although rare, malakoplakia is one of many potential causes of diarrhea in a transplant patient. The present case indicates that malakoplakia may be associated with chronic diarrhea, even if there are no macroscopic lesions seen during colonoscopy. |
| format | Article |
| id | doaj-art-b6b9c7043bdc436f8a673cc46eb1e3ca |
| institution | OA Journals |
| issn | 0835-7900 |
| language | English |
| publishDate | 2007-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-b6b9c7043bdc436f8a673cc46eb1e3ca2025-08-20T02:23:11ZengWileyCanadian Journal of Gastroenterology0835-79002007-01-01211175375510.1155/2007/256031Colonic Malakoplakia in a Liver Transplant RecipientPeter TW Kim0Jennifer E Davis1Siegfried R Erb2Eric M Yoshida3Urs P Steinbrecher4Department of Surgery, University of British Columbia, Vancouver, British Columbia, CanadaDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, CanadaDivision of Gastroenterology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, CanadaDivision of Gastroenterology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, CanadaDivision of Gastroenterology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, CanadaMalakoplakia is a rare inflammatory condition seen in transplant patients. There are two previously reported cases of malakoplakia involving the gastrointestinal tract in liver transplant patients. The present paper reports a case of colonic malakoplakia in a 58-year-old woman, a liver transplant recipient who was receiving immunosuppressive drugs. She presented with chronic diarrhea while on tacrolimus. There was no history of antecedent infection. Colonoscopy showed patchy mucosal edema, but no discrete yellow plaques or nodules. The diagnosis was made by colon biopsies, which showed chronic inflammation with many histiocytes containing Michaelis-Gutmann bodies. Although rare, malakoplakia is one of many potential causes of diarrhea in a transplant patient. The present case indicates that malakoplakia may be associated with chronic diarrhea, even if there are no macroscopic lesions seen during colonoscopy.http://dx.doi.org/10.1155/2007/256031 |
| spellingShingle | Peter TW Kim Jennifer E Davis Siegfried R Erb Eric M Yoshida Urs P Steinbrecher Colonic Malakoplakia in a Liver Transplant Recipient Canadian Journal of Gastroenterology |
| title | Colonic Malakoplakia in a Liver Transplant Recipient |
| title_full | Colonic Malakoplakia in a Liver Transplant Recipient |
| title_fullStr | Colonic Malakoplakia in a Liver Transplant Recipient |
| title_full_unstemmed | Colonic Malakoplakia in a Liver Transplant Recipient |
| title_short | Colonic Malakoplakia in a Liver Transplant Recipient |
| title_sort | colonic malakoplakia in a liver transplant recipient |
| url | http://dx.doi.org/10.1155/2007/256031 |
| work_keys_str_mv | AT petertwkim colonicmalakoplakiainalivertransplantrecipient AT jenniferedavis colonicmalakoplakiainalivertransplantrecipient AT siegfriedrerb colonicmalakoplakiainalivertransplantrecipient AT ericmyoshida colonicmalakoplakiainalivertransplantrecipient AT urspsteinbrecher colonicmalakoplakiainalivertransplantrecipient |