Lemierre's syndrome diagnosed using bedside ultrasound in the emergency department

Background: Lemierre's syndrome (LS) is a rare disease, typically occurring after a recent oropharyngeal infection. It is characterized by septic thrombophlebitis of the internal jugular (IJ) vein and bacteremia with metastatic septic emboli. Computed tomography (CT) of the neck with intravenou...

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Main Authors: Anis Adnani, Wesley Eilbert
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:JEM Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2773232024000658
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author Anis Adnani
Wesley Eilbert
author_facet Anis Adnani
Wesley Eilbert
author_sort Anis Adnani
collection DOAJ
description Background: Lemierre's syndrome (LS) is a rare disease, typically occurring after a recent oropharyngeal infection. It is characterized by septic thrombophlebitis of the internal jugular (IJ) vein and bacteremia with metastatic septic emboli. Computed tomography (CT) of the neck with intravenous contrast is the imaging study of choice to diagnose the IJ vein thrombosis present with LS. Case report: We present the case of an 18-year-old male who presented to the emergency department (ED) with right sided neck pain and shortness of breath. He had been seen in the ED two days earlier complaining of sore throat and was diagnosed with a viral infection. CT examinations of the neck and chest with intravenous contrast found multifocal bilateral nodular pulmonary densities with some soft tissue stranding adjacent to the right carotid sheath. No intraluminal filling defects of the right IJ vein were noted. A bedside ultrasound revealed a non-compressible hyperechoic thrombus in the right IJ vein, confirming the diagnosis of LS. To our knowledge, this is only the second reported case of LS diagnosed using bedside ultrasound that was initially missed on CT.Why should an emergency physician be aware of this? Rapid recognition of LS, a potentially fatal illness, is paramount to optimize outcome. Bedside ultrasound is a useful tool available to emergency physicians to diagnose this disease and initiate prompt treatment.
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spelling doaj-art-b6ad6bba2cf9468c988104ada9b3bd7e2025-08-20T02:00:32ZengElsevierJEM Reports2773-23202025-03-014110013510.1016/j.jemrpt.2024.100135Lemierre's syndrome diagnosed using bedside ultrasound in the emergency departmentAnis Adnani0Wesley Eilbert1Department of Emergency Medicine, Lutheran General Hospital, 1775 Dempster St, Park Ridge, IL, 60068, USADepartment of Emergency Medicine, University of Illinois Chicago, College of Medicine, Room 469 COME, 1819 West Polk St. Chicago, IL, 60612, USA; Corresponding author.Background: Lemierre's syndrome (LS) is a rare disease, typically occurring after a recent oropharyngeal infection. It is characterized by septic thrombophlebitis of the internal jugular (IJ) vein and bacteremia with metastatic septic emboli. Computed tomography (CT) of the neck with intravenous contrast is the imaging study of choice to diagnose the IJ vein thrombosis present with LS. Case report: We present the case of an 18-year-old male who presented to the emergency department (ED) with right sided neck pain and shortness of breath. He had been seen in the ED two days earlier complaining of sore throat and was diagnosed with a viral infection. CT examinations of the neck and chest with intravenous contrast found multifocal bilateral nodular pulmonary densities with some soft tissue stranding adjacent to the right carotid sheath. No intraluminal filling defects of the right IJ vein were noted. A bedside ultrasound revealed a non-compressible hyperechoic thrombus in the right IJ vein, confirming the diagnosis of LS. To our knowledge, this is only the second reported case of LS diagnosed using bedside ultrasound that was initially missed on CT.Why should an emergency physician be aware of this? Rapid recognition of LS, a potentially fatal illness, is paramount to optimize outcome. Bedside ultrasound is a useful tool available to emergency physicians to diagnose this disease and initiate prompt treatment.http://www.sciencedirect.com/science/article/pii/S2773232024000658Lemierre's syndromeLemierre syndromeInternal jugular vein thrombosisBedside ultrasoundPoint of care ultrasound
spellingShingle Anis Adnani
Wesley Eilbert
Lemierre's syndrome diagnosed using bedside ultrasound in the emergency department
JEM Reports
Lemierre's syndrome
Lemierre syndrome
Internal jugular vein thrombosis
Bedside ultrasound
Point of care ultrasound
title Lemierre's syndrome diagnosed using bedside ultrasound in the emergency department
title_full Lemierre's syndrome diagnosed using bedside ultrasound in the emergency department
title_fullStr Lemierre's syndrome diagnosed using bedside ultrasound in the emergency department
title_full_unstemmed Lemierre's syndrome diagnosed using bedside ultrasound in the emergency department
title_short Lemierre's syndrome diagnosed using bedside ultrasound in the emergency department
title_sort lemierre s syndrome diagnosed using bedside ultrasound in the emergency department
topic Lemierre's syndrome
Lemierre syndrome
Internal jugular vein thrombosis
Bedside ultrasound
Point of care ultrasound
url http://www.sciencedirect.com/science/article/pii/S2773232024000658
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AT wesleyeilbert lemierressyndromediagnosedusingbedsideultrasoundintheemergencydepartment