Phytochemical Insights and Therapeutic Potential of <i>Chamaenerion angustifolium</i> and <i>Chamaenerion latifolium</i>

The <i>Chamaenerion</i> genus, particularly <i>Chamaenerion angustifolium</i> and <i>Chamaenerion latifolium</i>, is recognized for its rich phytochemical composition and extensive medicinal properties. These species are abundant in polyphenols, flavonoids, and ta...

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Main Authors: Akmaral Kozhantayeva, Zhanar Iskakova, Manshuk Ibrayeva, Ardak Sapiyeva, Moldir Arkharbekova, Yerbolat Tashenov
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Molecules
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Online Access:https://www.mdpi.com/1420-3049/30/5/1186
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author Akmaral Kozhantayeva
Zhanar Iskakova
Manshuk Ibrayeva
Ardak Sapiyeva
Moldir Arkharbekova
Yerbolat Tashenov
author_facet Akmaral Kozhantayeva
Zhanar Iskakova
Manshuk Ibrayeva
Ardak Sapiyeva
Moldir Arkharbekova
Yerbolat Tashenov
author_sort Akmaral Kozhantayeva
collection DOAJ
description The <i>Chamaenerion</i> genus, particularly <i>Chamaenerion angustifolium</i> and <i>Chamaenerion latifolium</i>, is recognized for its rich phytochemical composition and extensive medicinal properties. These species are abundant in polyphenols, flavonoids, and tannins, which contribute to their potent antioxidant, antimicrobial, and anticancer activities. This review provides a comprehensive analysis of their phytochemical constituents, with an emphasis on how processing methods, including fermentation, influence bioactivity. Notably, fermentation enhances the levels of key bioactive compounds, such as oenothein B, gallic acid, and ellagic acid, thereby increasing their pharmacological potential. Additionally, this review evaluates the biological activities of <i>Chamaenerion</i> species in relation to their chemical composition, while also considering the limitations of current studies, such as the lack of in vivo or clinical trials. The literature for this review was sourced from scientific databases, including PubMed, Scopus, and ScienceDirect, covering research from 2010 to 2024. Future studies should focus on optimizing extraction methods, elucidating synergistic bioactivities, and conducting in-depth clinical trials to validate their efficacy and safety.
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spelling doaj-art-b6a0104b0be847da95eb8cfc5f3a67032025-08-20T02:52:42ZengMDPI AGMolecules1420-30492025-03-01305118610.3390/molecules30051186Phytochemical Insights and Therapeutic Potential of <i>Chamaenerion angustifolium</i> and <i>Chamaenerion latifolium</i>Akmaral Kozhantayeva0Zhanar Iskakova1Manshuk Ibrayeva2Ardak Sapiyeva3Moldir Arkharbekova4Yerbolat Tashenov5Research Institute of New Chemical Technologies, L.N. Gumilyov Eurasian National University, Satpayev Street 2, Astana 010000, KazakhstanResearch Institute of New Chemical Technologies, L.N. Gumilyov Eurasian National University, Satpayev Street 2, Astana 010000, KazakhstanFaculty of Science and Technology, Yessenov University, Aktau 130000, KazakhstanDepartment of General and Biological Chemistry, NJSC “Astana Medical University”, Astana 010000, KazakhstanDepartment of Chemistry, Faculty of Natural Sciences, L.N. Gumilyov Eurasian National University, Satpayev Street 2, Astana 010000, KazakhstanResearch Institute of New Chemical Technologies, L.N. Gumilyov Eurasian National University, Satpayev Street 2, Astana 010000, KazakhstanThe <i>Chamaenerion</i> genus, particularly <i>Chamaenerion angustifolium</i> and <i>Chamaenerion latifolium</i>, is recognized for its rich phytochemical composition and extensive medicinal properties. These species are abundant in polyphenols, flavonoids, and tannins, which contribute to their potent antioxidant, antimicrobial, and anticancer activities. This review provides a comprehensive analysis of their phytochemical constituents, with an emphasis on how processing methods, including fermentation, influence bioactivity. Notably, fermentation enhances the levels of key bioactive compounds, such as oenothein B, gallic acid, and ellagic acid, thereby increasing their pharmacological potential. Additionally, this review evaluates the biological activities of <i>Chamaenerion</i> species in relation to their chemical composition, while also considering the limitations of current studies, such as the lack of in vivo or clinical trials. The literature for this review was sourced from scientific databases, including PubMed, Scopus, and ScienceDirect, covering research from 2010 to 2024. Future studies should focus on optimizing extraction methods, elucidating synergistic bioactivities, and conducting in-depth clinical trials to validate their efficacy and safety.https://www.mdpi.com/1420-3049/30/5/1186<i>Chamaenerion angustifolium</i><i>Chamaenerion latifolium</i>phytochemicalsantioxidant activityantimicrobialantiproliferative
spellingShingle Akmaral Kozhantayeva
Zhanar Iskakova
Manshuk Ibrayeva
Ardak Sapiyeva
Moldir Arkharbekova
Yerbolat Tashenov
Phytochemical Insights and Therapeutic Potential of <i>Chamaenerion angustifolium</i> and <i>Chamaenerion latifolium</i>
Molecules
<i>Chamaenerion angustifolium</i>
<i>Chamaenerion latifolium</i>
phytochemicals
antioxidant activity
antimicrobial
antiproliferative
title Phytochemical Insights and Therapeutic Potential of <i>Chamaenerion angustifolium</i> and <i>Chamaenerion latifolium</i>
title_full Phytochemical Insights and Therapeutic Potential of <i>Chamaenerion angustifolium</i> and <i>Chamaenerion latifolium</i>
title_fullStr Phytochemical Insights and Therapeutic Potential of <i>Chamaenerion angustifolium</i> and <i>Chamaenerion latifolium</i>
title_full_unstemmed Phytochemical Insights and Therapeutic Potential of <i>Chamaenerion angustifolium</i> and <i>Chamaenerion latifolium</i>
title_short Phytochemical Insights and Therapeutic Potential of <i>Chamaenerion angustifolium</i> and <i>Chamaenerion latifolium</i>
title_sort phytochemical insights and therapeutic potential of i chamaenerion angustifolium i and i chamaenerion latifolium i
topic <i>Chamaenerion angustifolium</i>
<i>Chamaenerion latifolium</i>
phytochemicals
antioxidant activity
antimicrobial
antiproliferative
url https://www.mdpi.com/1420-3049/30/5/1186
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