Chemoprevention of Gastric Cancer: Metformin
Metformin is a first-line anti-diabetic drug that has been widely used in patients with type 2 diabetes. Many population-based epidemiologic studies have shown that metformin treatment is associated with decreased risk for various cancers. Recent epidemiologic studies showed that the use of metformi...
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| Format: | Article |
| Language: | English |
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Korean College of Helicobacter and Upper Gastrointestinal Research
2017-12-01
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| Series: | The Korean Journal of Helicobacter and Upper Gastrointestinal Research |
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| Online Access: | http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2017.17.4.179 |
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| _version_ | 1849407929374998528 |
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| author | Young-Il Kim Soo-Jeong Cho |
| author_facet | Young-Il Kim Soo-Jeong Cho |
| author_sort | Young-Il Kim |
| collection | DOAJ |
| description | Metformin is a first-line anti-diabetic drug that has been widely used in patients with type 2 diabetes. Many population-based epidemiologic studies have shown that metformin treatment is associated with decreased risk for various cancers. Recent epidemiologic studies showed that the use of metformin was associated with a reduction in gastric cancer risk, especially in patients with type 2 diabetes who used metformin for long periods of time (>2∼3 years). Currently, there are no registered clinical trials investigating the anti-cancer effect of metformin in gastric cancer; hence, further well-designed clinical trials are required. Herein, we review the literature regarding the use of metformin for the prevention of gastric cancer. |
| format | Article |
| id | doaj-art-b6967ef26a3f4f0dabe5bc5efc5a1c6d |
| institution | Kabale University |
| issn | 1738-3331 |
| language | English |
| publishDate | 2017-12-01 |
| publisher | Korean College of Helicobacter and Upper Gastrointestinal Research |
| record_format | Article |
| series | The Korean Journal of Helicobacter and Upper Gastrointestinal Research |
| spelling | doaj-art-b6967ef26a3f4f0dabe5bc5efc5a1c6d2025-08-20T03:35:54ZengKorean College of Helicobacter and Upper Gastrointestinal ResearchThe Korean Journal of Helicobacter and Upper Gastrointestinal Research1738-33312017-12-0117417918410.7704/kjhugr.2017.17.4.179kjhugr.2017.17.4.179Chemoprevention of Gastric Cancer: MetforminYoung-Il Kim0Soo-Jeong Cho1Center for Gastric Cancer, National Cancer Center, Goyang, KoreaCenter for Gastric Cancer, National Cancer Center, Goyang, KoreaMetformin is a first-line anti-diabetic drug that has been widely used in patients with type 2 diabetes. Many population-based epidemiologic studies have shown that metformin treatment is associated with decreased risk for various cancers. Recent epidemiologic studies showed that the use of metformin was associated with a reduction in gastric cancer risk, especially in patients with type 2 diabetes who used metformin for long periods of time (>2∼3 years). Currently, there are no registered clinical trials investigating the anti-cancer effect of metformin in gastric cancer; hence, further well-designed clinical trials are required. Herein, we review the literature regarding the use of metformin for the prevention of gastric cancer.http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2017.17.4.179ChemopreventionMetforminStomach neoplasms |
| spellingShingle | Young-Il Kim Soo-Jeong Cho Chemoprevention of Gastric Cancer: Metformin The Korean Journal of Helicobacter and Upper Gastrointestinal Research Chemoprevention Metformin Stomach neoplasms |
| title | Chemoprevention of Gastric Cancer: Metformin |
| title_full | Chemoprevention of Gastric Cancer: Metformin |
| title_fullStr | Chemoprevention of Gastric Cancer: Metformin |
| title_full_unstemmed | Chemoprevention of Gastric Cancer: Metformin |
| title_short | Chemoprevention of Gastric Cancer: Metformin |
| title_sort | chemoprevention of gastric cancer metformin |
| topic | Chemoprevention Metformin Stomach neoplasms |
| url | http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2017.17.4.179 |
| work_keys_str_mv | AT youngilkim chemopreventionofgastriccancermetformin AT soojeongcho chemopreventionofgastriccancermetformin |