Packaged release and targeted delivery of cytokines by migrasomes in circulation

Abstract In dynamic systems like the circulatory system, establishing localized cytokine gradients is challenging. Upon lipopolysaccharide (LPS) stimulation, we observed that monocytes release numerous migrasomes enriched with inflammatory cytokines, such as TNF-α and IL-6. These cytokines are trans...

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Bibliographic Details
Main Authors: Haifeng Jiao, Xiaopeng Li, Ying Li, Ziyi Guo, Yuzhuo Yang, Yiqun Luo, Xiaoyu Hu, Li Yu
Format: Article
Language:English
Published: Nature Publishing Group 2024-12-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-024-00749-x
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