Cardiovascular risk in newly diagnosed patients with type 2 diabetes mellitus: a nationwide, facility-based, cross-sectional study in Bangladesh
Aims: Evidence on cardiovascular (CV) risk stratification in Bangladeshi patients with type 2 diabetes mellitus (T2DM) who are asymptomatic for cardiovascular disease (CVD) is limited. This study aimed to assess the 10-year CV risk in newly diagnosed patients with T2DM. Methods: In 2023, a cross-sec...
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Elsevier
2025-06-01
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| Series: | International Journal of Cardiology. Cardiovascular Risk and Prevention |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772487525000376 |
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| author | A.B.M. Kamrul-Hasan Muhammad Shah Alam Marufa Mustari Mohammad Abdul Hannan Emran Ur Rashid Chowdhury Sumon Rahman Chowdhury Md. Abu Jar Gaffar Swapan Kumar Singha Choman Abdullah Mohana Ershad Mondal Md. Shahinur Rahman Mohammad Motiur Rahman Sourav Sarker Md. Azizul Hoque Md. Rashedul Islam Md. Abdul Bari Robel Shahryar Ahmad Ahmed Ifrad Bin Raunak Nur-A-Musabber Md. Mostofa Kaisar Shahjada Selim |
| author_facet | A.B.M. Kamrul-Hasan Muhammad Shah Alam Marufa Mustari Mohammad Abdul Hannan Emran Ur Rashid Chowdhury Sumon Rahman Chowdhury Md. Abu Jar Gaffar Swapan Kumar Singha Choman Abdullah Mohana Ershad Mondal Md. Shahinur Rahman Mohammad Motiur Rahman Sourav Sarker Md. Azizul Hoque Md. Rashedul Islam Md. Abdul Bari Robel Shahryar Ahmad Ahmed Ifrad Bin Raunak Nur-A-Musabber Md. Mostofa Kaisar Shahjada Selim |
| author_sort | A.B.M. Kamrul-Hasan |
| collection | DOAJ |
| description | Aims: Evidence on cardiovascular (CV) risk stratification in Bangladeshi patients with type 2 diabetes mellitus (T2DM) who are asymptomatic for cardiovascular disease (CVD) is limited. This study aimed to assess the 10-year CV risk in newly diagnosed patients with T2DM. Methods: In 2023, a cross-sectional study was carried out at endocrinology clinics in tertiary hospitals throughout Bangladesh, involving newly diagnosed patients with T2DM aged 25 to 84 who had no prior history of CVD and were asymptomatic for the condition. CV risk was assessed and classified using QRISK3. Results: 1617 newly diagnosed patients with T2DM (age 44.92 ± 11.84 years, male 49.5 %) were analyzed. Their median QRISK3 score was 11.0 %, with 46.5 % at low, 25.7 % at moderate, and 27.8 % at high 10-year CV risk, respectively. The QRISK3 score increased with age for both men and women, with men consistently scoring higher than women in every age group. Among the age groups 25–39, 40–64, and 65–84, the percentages of patients with high 10-year CV risk were 3.3 %, 34.0 %, and 94.5 %, respectively. The median relative risk (RR) of CVD was 4.3. RR decreased with age for both sexes, and men had a lower RR than women across all age groups. A sleep duration of 6–9 h was associated with a lower 10-year CV risk. Conclusions: Many newly diagnosed Bangladeshi patients with T2DM have substantial CV risk. QRISK3 can assist clinicians in predicting 10-year CV risk and choosing appropriate treatments to prevent CVD. |
| format | Article |
| id | doaj-art-b68eaad11f9a4fe6a9c577df3fa17442 |
| institution | OA Journals |
| issn | 2772-4875 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Cardiology. Cardiovascular Risk and Prevention |
| spelling | doaj-art-b68eaad11f9a4fe6a9c577df3fa174422025-08-20T01:51:53ZengElsevierInternational Journal of Cardiology. Cardiovascular Risk and Prevention2772-48752025-06-012520039910.1016/j.ijcrp.2025.200399Cardiovascular risk in newly diagnosed patients with type 2 diabetes mellitus: a nationwide, facility-based, cross-sectional study in BangladeshA.B.M. Kamrul-Hasan0Muhammad Shah Alam1Marufa Mustari2Mohammad Abdul Hannan3Emran Ur Rashid Chowdhury4Sumon Rahman Chowdhury5Md. Abu Jar Gaffar6Swapan Kumar Singha7Choman Abdullah Mohana8Ershad Mondal9Md. Shahinur Rahman10Mohammad Motiur Rahman11Sourav Sarker12Md. Azizul Hoque13Md. Rashedul Islam14Md. Abdul Bari Robel15Shahryar Ahmad16Ahmed Ifrad Bin Raunak17 Nur-A-Musabber18Md. Mostofa Kaisar19Shahjada Selim20Department of Endocrinology, Mymensingh Medical College, Mymensingh, Bangladesh; Corresponding author. Department of Endocrinology, Mymensingh Medical College, Mymensingh Sadar, Mymensingh 2200, Bangladesh.Department of Medicine, Army Medical College Cumilla, Cumilla, BangladeshDepartment of Endocrinology, Bangabandhu Sheikh Mujib Medical University, Dhaka, BangladeshDepartment of Endocrinology, North East Medical College, Sylhet, BangladeshDepartment of Endocrinology & Diabetology, Evercare Hospital, Chattogram, BangladeshDepartment of Diabetes, Endocrinology and Metabolism, Chittagong Diabetic General Hospital, Chattogram, BangladeshDepartment of Pathology, Naogaon Medical College, Naogaon, BangladeshDepartment of Medicine, Habiganj Medical College, Habiganj, BangladeshDepartment of Endocrinology, Mymensingh Medical College Hospital, Mymensingh, BangladeshDepartment of Endocrinology, Mymensingh Medical College Hospital, Mymensingh, BangladeshDepartment of Diabetes and Endocrinology, Diabetic Association Hospital, Pabna, BangladeshDepartment of Medicine, Rajshahi Medical College Hospital, Rajshahi, BangladeshDepartment of Medicine, Boalkhali Upazila Health Complex, Chattogram, BangladeshDepartment of Endocrinology, Shaheed Tajuddin Ahmad Medical College, Gazipur, BangladeshDepartment of Neurology, BIRDEM General Hospital, Dhaka, BangladeshDepartment of Endocrinology, Cumilla Medical College Hospital, Cumilla, BangladeshDepartment of Endocrinology, Comilla Medical College, Cumilla, BangladeshDepartment of Endocrinology, Shaheed Suhrawardy Medical College and Hospital, Dhaka, BangladeshDepartment of Endocrinology, Mymensingh Medical College Hospital, Mymensingh, BangladeshDepartment of Endocrinology, Sheikh Fazilatunnessa Mujib Memorial KPJ Specialized Hospital, Kasimpur, Gazipur, BangladeshDepartment of Endocrinology, Bangabandhu Sheikh Mujib Medical University, Dhaka, BangladeshAims: Evidence on cardiovascular (CV) risk stratification in Bangladeshi patients with type 2 diabetes mellitus (T2DM) who are asymptomatic for cardiovascular disease (CVD) is limited. This study aimed to assess the 10-year CV risk in newly diagnosed patients with T2DM. Methods: In 2023, a cross-sectional study was carried out at endocrinology clinics in tertiary hospitals throughout Bangladesh, involving newly diagnosed patients with T2DM aged 25 to 84 who had no prior history of CVD and were asymptomatic for the condition. CV risk was assessed and classified using QRISK3. Results: 1617 newly diagnosed patients with T2DM (age 44.92 ± 11.84 years, male 49.5 %) were analyzed. Their median QRISK3 score was 11.0 %, with 46.5 % at low, 25.7 % at moderate, and 27.8 % at high 10-year CV risk, respectively. The QRISK3 score increased with age for both men and women, with men consistently scoring higher than women in every age group. Among the age groups 25–39, 40–64, and 65–84, the percentages of patients with high 10-year CV risk were 3.3 %, 34.0 %, and 94.5 %, respectively. The median relative risk (RR) of CVD was 4.3. RR decreased with age for both sexes, and men had a lower RR than women across all age groups. A sleep duration of 6–9 h was associated with a lower 10-year CV risk. Conclusions: Many newly diagnosed Bangladeshi patients with T2DM have substantial CV risk. QRISK3 can assist clinicians in predicting 10-year CV risk and choosing appropriate treatments to prevent CVD.http://www.sciencedirect.com/science/article/pii/S277248752500037610-Year cardiovascular riskQRISK3Risk assessmentSleepType 2 diabetes |
| spellingShingle | A.B.M. Kamrul-Hasan Muhammad Shah Alam Marufa Mustari Mohammad Abdul Hannan Emran Ur Rashid Chowdhury Sumon Rahman Chowdhury Md. Abu Jar Gaffar Swapan Kumar Singha Choman Abdullah Mohana Ershad Mondal Md. Shahinur Rahman Mohammad Motiur Rahman Sourav Sarker Md. Azizul Hoque Md. Rashedul Islam Md. Abdul Bari Robel Shahryar Ahmad Ahmed Ifrad Bin Raunak Nur-A-Musabber Md. Mostofa Kaisar Shahjada Selim Cardiovascular risk in newly diagnosed patients with type 2 diabetes mellitus: a nationwide, facility-based, cross-sectional study in Bangladesh International Journal of Cardiology. Cardiovascular Risk and Prevention 10-Year cardiovascular risk QRISK3 Risk assessment Sleep Type 2 diabetes |
| title | Cardiovascular risk in newly diagnosed patients with type 2 diabetes mellitus: a nationwide, facility-based, cross-sectional study in Bangladesh |
| title_full | Cardiovascular risk in newly diagnosed patients with type 2 diabetes mellitus: a nationwide, facility-based, cross-sectional study in Bangladesh |
| title_fullStr | Cardiovascular risk in newly diagnosed patients with type 2 diabetes mellitus: a nationwide, facility-based, cross-sectional study in Bangladesh |
| title_full_unstemmed | Cardiovascular risk in newly diagnosed patients with type 2 diabetes mellitus: a nationwide, facility-based, cross-sectional study in Bangladesh |
| title_short | Cardiovascular risk in newly diagnosed patients with type 2 diabetes mellitus: a nationwide, facility-based, cross-sectional study in Bangladesh |
| title_sort | cardiovascular risk in newly diagnosed patients with type 2 diabetes mellitus a nationwide facility based cross sectional study in bangladesh |
| topic | 10-Year cardiovascular risk QRISK3 Risk assessment Sleep Type 2 diabetes |
| url | http://www.sciencedirect.com/science/article/pii/S2772487525000376 |
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