Insights and progress on postoperative analgesia of radical gastrectomy for gastric cancer: a comprehensive review
Gastric cancer is a common and highly lethal malignancy of the digestive system, with surgical resection as the primary treatment approach. However, postoperative analgesia management remains a major clinical challenge. Postoperative pain not only affects recovery speed but may also lead to complica...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-06-01
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| Series: | Frontiers in Pain Research |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpain.2025.1601220/full |
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| author | Linghui Li Yuanyuan Zhao Huan Chen Jianqin Zhao Mengjun Dai Qi Wang Jie Lv Wei Wang |
| author_facet | Linghui Li Yuanyuan Zhao Huan Chen Jianqin Zhao Mengjun Dai Qi Wang Jie Lv Wei Wang |
| author_sort | Linghui Li |
| collection | DOAJ |
| description | Gastric cancer is a common and highly lethal malignancy of the digestive system, with surgical resection as the primary treatment approach. However, postoperative analgesia management remains a major clinical challenge. Postoperative pain not only affects recovery speed but may also lead to complications, thereby influencing prognosis. Recent research on postoperative pain following gastric cancer surgery has expanded, exploring various analgesic methods, including pharmacological therapy, neuraxial blocks, and non-pharmacological approaches, with growing emphasis on individualized analgesia protocols. Despite the proposal of multiple analgesic techniques, current research indicates that their effectiveness and safety are still inadequately assessed in clinical applications. This review aims to discuss the physiological mechanisms of postoperative pain following gastric cancer surgery, modern analgesic strategies, and related research, to provide a theoretical basis and clinical guidance for improving postoperative quality of life. |
| format | Article |
| id | doaj-art-b68c7202ecb4478eaf49d603732261d1 |
| institution | OA Journals |
| issn | 2673-561X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pain Research |
| spelling | doaj-art-b68c7202ecb4478eaf49d603732261d12025-08-20T02:37:41ZengFrontiers Media S.A.Frontiers in Pain Research2673-561X2025-06-01610.3389/fpain.2025.16012201601220Insights and progress on postoperative analgesia of radical gastrectomy for gastric cancer: a comprehensive reviewLinghui Li0Yuanyuan Zhao1Huan Chen2Jianqin Zhao3Mengjun Dai4Qi Wang5Jie Lv6Wei Wang7Department of Surgery and Anesthesiology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nangjing, ChinaDepartment of Anesthesiology, Huainan First People’s Hospital, The First Affiliated Hospital of Anhui University of Science and Technology, Huainan, ChinaDepartment of Surgery and Anesthesiology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nangjing, ChinaDepartment of Surgery and Anesthesiology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nangjing, ChinaDepartment of Surgery and Anesthesiology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nangjing, ChinaDepartment of Surgery and Anesthesiology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nangjing, ChinaDepartment of Surgery and Anesthesiology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nangjing, ChinaDepartment of Surgery and Anesthesiology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nangjing, ChinaGastric cancer is a common and highly lethal malignancy of the digestive system, with surgical resection as the primary treatment approach. However, postoperative analgesia management remains a major clinical challenge. Postoperative pain not only affects recovery speed but may also lead to complications, thereby influencing prognosis. Recent research on postoperative pain following gastric cancer surgery has expanded, exploring various analgesic methods, including pharmacological therapy, neuraxial blocks, and non-pharmacological approaches, with growing emphasis on individualized analgesia protocols. Despite the proposal of multiple analgesic techniques, current research indicates that their effectiveness and safety are still inadequately assessed in clinical applications. This review aims to discuss the physiological mechanisms of postoperative pain following gastric cancer surgery, modern analgesic strategies, and related research, to provide a theoretical basis and clinical guidance for improving postoperative quality of life.https://www.frontiersin.org/articles/10.3389/fpain.2025.1601220/fullstomach neoplasmsanalgesiapain managementpain mechanismsclinical studies as topic |
| spellingShingle | Linghui Li Yuanyuan Zhao Huan Chen Jianqin Zhao Mengjun Dai Qi Wang Jie Lv Wei Wang Insights and progress on postoperative analgesia of radical gastrectomy for gastric cancer: a comprehensive review Frontiers in Pain Research stomach neoplasms analgesia pain management pain mechanisms clinical studies as topic |
| title | Insights and progress on postoperative analgesia of radical gastrectomy for gastric cancer: a comprehensive review |
| title_full | Insights and progress on postoperative analgesia of radical gastrectomy for gastric cancer: a comprehensive review |
| title_fullStr | Insights and progress on postoperative analgesia of radical gastrectomy for gastric cancer: a comprehensive review |
| title_full_unstemmed | Insights and progress on postoperative analgesia of radical gastrectomy for gastric cancer: a comprehensive review |
| title_short | Insights and progress on postoperative analgesia of radical gastrectomy for gastric cancer: a comprehensive review |
| title_sort | insights and progress on postoperative analgesia of radical gastrectomy for gastric cancer a comprehensive review |
| topic | stomach neoplasms analgesia pain management pain mechanisms clinical studies as topic |
| url | https://www.frontiersin.org/articles/10.3389/fpain.2025.1601220/full |
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