Oncolytic virotherapy and the current approaches in veterinary medicine

Cancer has an increasing incidence worldwide in humans and animals. In addition to traditional treatments such as surgery, radiotherapy, and chemotherapy, there is a search for new treatment strategies for cancer treatment. Oncolytic virotherapy arouses great interest in human medicine with the deve...

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Main Authors: Bengu Bilgic, Banu Dokuzeylul, Mehmet Or
Format: Article
Language:English
Published: German Multidisciplinary Publishing Center (GMPC) 2022-01-01
Series:German Journal of Veterinary Research
Online Access:https://doi.org/10.51585/gjvr.2022.2.0032
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author Bengu Bilgic
Banu Dokuzeylul
Mehmet Or
author_facet Bengu Bilgic
Banu Dokuzeylul
Mehmet Or
author_sort Bengu Bilgic
collection DOAJ
description Cancer has an increasing incidence worldwide in humans and animals. In addition to traditional treatments such as surgery, radiotherapy, and chemotherapy, there is a search for new treatment strategies for cancer treatment. Oncolytic virotherapy arouses great interest in human medicine with the development of biotechnology and increasing knowledge about virus-cell interactions in recent years. Many in-vivo and in-vitro studies have led to the development of a United States Food and Drug Administration (FDA)-approved, genetically modified oncolytic viral therapy. Based on the studies in human medicine, some clinical trials have also been carried out with oncolytic virotherapy in veterinary medicine. But the studies in cats and dogs are very limited. This review aims to compare the development of oncolytic virotherapy in human and veterinary medicine with current studies and to draw attention to the fact that virotherapy can be used as a treatment option for various tumoral diseases in veterinary medicine in the future.
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language English
publishDate 2022-01-01
publisher German Multidisciplinary Publishing Center (GMPC)
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series German Journal of Veterinary Research
spelling doaj-art-b6837d6d6430464d9f92291d4f941b7a2025-08-20T03:05:16ZengGerman Multidisciplinary Publishing Center (GMPC)German Journal of Veterinary Research2703-13222022-01-01172710.51585/gjvr.2022.2.0032Oncolytic virotherapy and the current approaches in veterinary medicineBengu BilgicBanu DokuzeylulMehmet OrCancer has an increasing incidence worldwide in humans and animals. In addition to traditional treatments such as surgery, radiotherapy, and chemotherapy, there is a search for new treatment strategies for cancer treatment. Oncolytic virotherapy arouses great interest in human medicine with the development of biotechnology and increasing knowledge about virus-cell interactions in recent years. Many in-vivo and in-vitro studies have led to the development of a United States Food and Drug Administration (FDA)-approved, genetically modified oncolytic viral therapy. Based on the studies in human medicine, some clinical trials have also been carried out with oncolytic virotherapy in veterinary medicine. But the studies in cats and dogs are very limited. This review aims to compare the development of oncolytic virotherapy in human and veterinary medicine with current studies and to draw attention to the fact that virotherapy can be used as a treatment option for various tumoral diseases in veterinary medicine in the future.https://doi.org/10.51585/gjvr.2022.2.0032
spellingShingle Bengu Bilgic
Banu Dokuzeylul
Mehmet Or
Oncolytic virotherapy and the current approaches in veterinary medicine
German Journal of Veterinary Research
title Oncolytic virotherapy and the current approaches in veterinary medicine
title_full Oncolytic virotherapy and the current approaches in veterinary medicine
title_fullStr Oncolytic virotherapy and the current approaches in veterinary medicine
title_full_unstemmed Oncolytic virotherapy and the current approaches in veterinary medicine
title_short Oncolytic virotherapy and the current approaches in veterinary medicine
title_sort oncolytic virotherapy and the current approaches in veterinary medicine
url https://doi.org/10.51585/gjvr.2022.2.0032
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