Primary malignant teratoma of the mediastinum with poor outcome: A case report
Introduction. About 5%–10% of mediastinal tumors in adults are teratomas and about 85% of them are benign. Case report. We report a case of extragonadal malignant teratoma in a 39-year old man. The computed tomography (CT) scan of the chest revealed the soft-tissue density mass in the middle lobe of...
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| Format: | Article |
| Language: | English |
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2018-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2018/0042-84501600386S.pdf |
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| author | Sazdanić-Velikić Danica Škrbić Dušan Považan Đorđe Đurić Mirna Vučković Dejan Sečen Nevena |
| author_facet | Sazdanić-Velikić Danica Škrbić Dušan Považan Đorđe Đurić Mirna Vučković Dejan Sečen Nevena |
| author_sort | Sazdanić-Velikić Danica |
| collection | DOAJ |
| description | Introduction. About 5%–10% of mediastinal tumors in adults are teratomas and about 85% of them are benign. Case report. We report a case of extragonadal malignant teratoma in a 39-year old man. The computed tomography (CT) scan of the chest revealed the soft-tissue density mass in the middle lobe of the lung. The posterolateral thoracotomy was performed and a mediastinal tumor of 25 cm was completely resected. Histopathological findings confirmed malignant teratoma. One month after the resection the positron emission tomography- computed tomography (PET/CT) scan of the whole body was performed and showed progression of the disease. Patient developed signs of the superior vena cava obstruction and received radiotherapy of the mediastinum and the metastatic lesion of the lumbal vertebra. After radiotherapy, the patient developed paraplegia and urinary incontinence and received the best supportive treatment. Conclusion. Primary extragonadal germ cell tumors have poor prognosis due to their relative chemoresistance and frequent findings of advanced disease after establishing the diagnosis. |
| format | Article |
| id | doaj-art-b6820197873144498e92db68d5431bb4 |
| institution | OA Journals |
| issn | 0042-8450 2406-0720 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-b6820197873144498e92db68d5431bb42025-08-20T02:23:11ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202018-01-0175883684010.2298/VSP160331386S0042-84501600386SPrimary malignant teratoma of the mediastinum with poor outcome: A case reportSazdanić-Velikić Danica0Škrbić Dušan1Považan Đorđe2Đurić Mirna3Vučković Dejan4Sečen Nevena5nemanemanemanemanemanemaIntroduction. About 5%–10% of mediastinal tumors in adults are teratomas and about 85% of them are benign. Case report. We report a case of extragonadal malignant teratoma in a 39-year old man. The computed tomography (CT) scan of the chest revealed the soft-tissue density mass in the middle lobe of the lung. The posterolateral thoracotomy was performed and a mediastinal tumor of 25 cm was completely resected. Histopathological findings confirmed malignant teratoma. One month after the resection the positron emission tomography- computed tomography (PET/CT) scan of the whole body was performed and showed progression of the disease. Patient developed signs of the superior vena cava obstruction and received radiotherapy of the mediastinum and the metastatic lesion of the lumbal vertebra. After radiotherapy, the patient developed paraplegia and urinary incontinence and received the best supportive treatment. Conclusion. Primary extragonadal germ cell tumors have poor prognosis due to their relative chemoresistance and frequent findings of advanced disease after establishing the diagnosis.http://www.doiserbia.nb.rs/img/doi/0042-8450/2018/0042-84501600386S.pdfteratomamediastinal neoplasmsdiagnostic techniques and proceduresthoracic surgery neoplasm metastasisradiotherapypalliative care |
| spellingShingle | Sazdanić-Velikić Danica Škrbić Dušan Považan Đorđe Đurić Mirna Vučković Dejan Sečen Nevena Primary malignant teratoma of the mediastinum with poor outcome: A case report Vojnosanitetski Pregled teratoma mediastinal neoplasms diagnostic techniques and procedures thoracic surgery neoplasm metastasis radiotherapy palliative care |
| title | Primary malignant teratoma of the mediastinum with poor outcome: A case report |
| title_full | Primary malignant teratoma of the mediastinum with poor outcome: A case report |
| title_fullStr | Primary malignant teratoma of the mediastinum with poor outcome: A case report |
| title_full_unstemmed | Primary malignant teratoma of the mediastinum with poor outcome: A case report |
| title_short | Primary malignant teratoma of the mediastinum with poor outcome: A case report |
| title_sort | primary malignant teratoma of the mediastinum with poor outcome a case report |
| topic | teratoma mediastinal neoplasms diagnostic techniques and procedures thoracic surgery neoplasm metastasis radiotherapy palliative care |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2018/0042-84501600386S.pdf |
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