Prevalence of Mycobacterium tuberculosis in Patients Suffering from Chronic Respiratory Diseases in a Tertiary Care Hospital Using Gene Xpert as the Diagnostic Tool
Background: Chronic respiratory diseases constitute a grave problem throughout the world and particularly in the middle- and low-income countries. The burden of these diseases leads to poor quality of life and disability of affected individuals leading to premature deaths and a great economic loss t...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2022-01-01
|
| Series: | Assam Journal of Internal Medicine |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/ajoim.ajoim_3_21 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849704359278936064 |
|---|---|
| author | Baishali Das Dina Raja |
| author_facet | Baishali Das Dina Raja |
| author_sort | Baishali Das |
| collection | DOAJ |
| description | Background:
Chronic respiratory diseases constitute a grave problem throughout the world and particularly in the middle- and low-income countries. The burden of these diseases leads to poor quality of life and disability of affected individuals leading to premature deaths and a great economic loss to their families and society. Tuberculosis remains one of the deadliest communicable diseases. Though culture is the gold standard for the diagnosis of tuberculosis, the long period of time required for a positive result leads to the transmission of the disease in the community.
Objective:
The study was conducted to study the prevalence of Mycobacterium tuberculosis in patients suffering from chronic respiratory diseases.
Materials and Methods:
Bronchoalveolar lavage fluid samples of patients with chronic respiratory diseases undergoing bronchoscopy were collected under aseptic conditions after obtaining approval from the Institutional Ethics Committee. Each sample was subjected to Ziehl Neelsen stain and Cartridge Based Nucleic Acid Amplification Test (CBNAAT) on Xpert MTB/RIF manufactured by Cepheid (Sunnyvale, CA).
Results:
Eighteen of 110 cases (16.36%) showed the presence of M. tuberculosis in the samples, of which rifampicin resistance was detected in 2 (11.11%) cases.
Conclusions:
M. tuberculosis remains a common underlying pathogen in the cases of chronic respiratory diseases. |
| format | Article |
| id | doaj-art-b67f69362ff748c1b602d31ff550e512 |
| institution | DOAJ |
| issn | 2278-8239 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Assam Journal of Internal Medicine |
| spelling | doaj-art-b67f69362ff748c1b602d31ff550e5122025-08-20T03:16:46ZengWolters Kluwer Medknow PublicationsAssam Journal of Internal Medicine2278-82392022-01-01121101310.4103/ajoim.ajoim_3_21Prevalence of Mycobacterium tuberculosis in Patients Suffering from Chronic Respiratory Diseases in a Tertiary Care Hospital Using Gene Xpert as the Diagnostic ToolBaishali DasDina RajaBackground: Chronic respiratory diseases constitute a grave problem throughout the world and particularly in the middle- and low-income countries. The burden of these diseases leads to poor quality of life and disability of affected individuals leading to premature deaths and a great economic loss to their families and society. Tuberculosis remains one of the deadliest communicable diseases. Though culture is the gold standard for the diagnosis of tuberculosis, the long period of time required for a positive result leads to the transmission of the disease in the community. Objective: The study was conducted to study the prevalence of Mycobacterium tuberculosis in patients suffering from chronic respiratory diseases. Materials and Methods: Bronchoalveolar lavage fluid samples of patients with chronic respiratory diseases undergoing bronchoscopy were collected under aseptic conditions after obtaining approval from the Institutional Ethics Committee. Each sample was subjected to Ziehl Neelsen stain and Cartridge Based Nucleic Acid Amplification Test (CBNAAT) on Xpert MTB/RIF manufactured by Cepheid (Sunnyvale, CA). Results: Eighteen of 110 cases (16.36%) showed the presence of M. tuberculosis in the samples, of which rifampicin resistance was detected in 2 (11.11%) cases. Conclusions: M. tuberculosis remains a common underlying pathogen in the cases of chronic respiratory diseases.https://journals.lww.com/10.4103/ajoim.ajoim_3_21chronic respiratory diseasesgene xpertmycobacterium tuberculosis |
| spellingShingle | Baishali Das Dina Raja Prevalence of Mycobacterium tuberculosis in Patients Suffering from Chronic Respiratory Diseases in a Tertiary Care Hospital Using Gene Xpert as the Diagnostic Tool Assam Journal of Internal Medicine chronic respiratory diseases gene xpert mycobacterium tuberculosis |
| title | Prevalence of Mycobacterium tuberculosis in Patients Suffering from Chronic Respiratory Diseases in a Tertiary Care Hospital Using Gene Xpert as the Diagnostic Tool |
| title_full | Prevalence of Mycobacterium tuberculosis in Patients Suffering from Chronic Respiratory Diseases in a Tertiary Care Hospital Using Gene Xpert as the Diagnostic Tool |
| title_fullStr | Prevalence of Mycobacterium tuberculosis in Patients Suffering from Chronic Respiratory Diseases in a Tertiary Care Hospital Using Gene Xpert as the Diagnostic Tool |
| title_full_unstemmed | Prevalence of Mycobacterium tuberculosis in Patients Suffering from Chronic Respiratory Diseases in a Tertiary Care Hospital Using Gene Xpert as the Diagnostic Tool |
| title_short | Prevalence of Mycobacterium tuberculosis in Patients Suffering from Chronic Respiratory Diseases in a Tertiary Care Hospital Using Gene Xpert as the Diagnostic Tool |
| title_sort | prevalence of mycobacterium tuberculosis in patients suffering from chronic respiratory diseases in a tertiary care hospital using gene xpert as the diagnostic tool |
| topic | chronic respiratory diseases gene xpert mycobacterium tuberculosis |
| url | https://journals.lww.com/10.4103/ajoim.ajoim_3_21 |
| work_keys_str_mv | AT baishalidas prevalenceofmycobacteriumtuberculosisinpatientssufferingfromchronicrespiratorydiseasesinatertiarycarehospitalusinggenexpertasthediagnostictool AT dinaraja prevalenceofmycobacteriumtuberculosisinpatientssufferingfromchronicrespiratorydiseasesinatertiarycarehospitalusinggenexpertasthediagnostictool |