Hematologic Chaos in Lupus Flare: A Case of Fulminant and Simultaneous Antiphospholipid, Anti-ADAMTS13, and Red Blood Cell Autoantibodies
Systemic lupus erythematosus may present with several distinct autoimmune phenomena simultaneously. We report a patient presenting with three serious hematologic disorders: thrombotic thrombocytopenic purpura, catastrophic antiphospholipid syndrome, and warm-type IgG red cell autoantibodies. The cas...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Rheumatology |
| Online Access: | http://dx.doi.org/10.1155/2020/8812550 |
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| author | Jafar Al-Mondhiry Caroline Y. Chen Michael H. Rosove |
| author_facet | Jafar Al-Mondhiry Caroline Y. Chen Michael H. Rosove |
| author_sort | Jafar Al-Mondhiry |
| collection | DOAJ |
| description | Systemic lupus erythematosus may present with several distinct autoimmune phenomena simultaneously. We report a patient presenting with three serious hematologic disorders: thrombotic thrombocytopenic purpura, catastrophic antiphospholipid syndrome, and warm-type IgG red cell autoantibodies. The case is an example of the complex clinical nature of lupus and the importance of accurately identifying individual complications in order to optimize management. |
| format | Article |
| id | doaj-art-b67d2271b6d641cba40c9e2aecb81aec |
| institution | DOAJ |
| issn | 2090-6889 2090-6897 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Rheumatology |
| spelling | doaj-art-b67d2271b6d641cba40c9e2aecb81aec2025-08-20T03:20:55ZengWileyCase Reports in Rheumatology2090-68892090-68972020-01-01202010.1155/2020/88125508812550Hematologic Chaos in Lupus Flare: A Case of Fulminant and Simultaneous Antiphospholipid, Anti-ADAMTS13, and Red Blood Cell AutoantibodiesJafar Al-Mondhiry0Caroline Y. Chen1Michael H. Rosove2UCLA David Geffen School of Medicine, Los Angeles, CA, USAUCLA David Geffen School of Medicine, Los Angeles, CA, USAUCLA David Geffen School of Medicine, Los Angeles, CA, USASystemic lupus erythematosus may present with several distinct autoimmune phenomena simultaneously. We report a patient presenting with three serious hematologic disorders: thrombotic thrombocytopenic purpura, catastrophic antiphospholipid syndrome, and warm-type IgG red cell autoantibodies. The case is an example of the complex clinical nature of lupus and the importance of accurately identifying individual complications in order to optimize management.http://dx.doi.org/10.1155/2020/8812550 |
| spellingShingle | Jafar Al-Mondhiry Caroline Y. Chen Michael H. Rosove Hematologic Chaos in Lupus Flare: A Case of Fulminant and Simultaneous Antiphospholipid, Anti-ADAMTS13, and Red Blood Cell Autoantibodies Case Reports in Rheumatology |
| title | Hematologic Chaos in Lupus Flare: A Case of Fulminant and Simultaneous Antiphospholipid, Anti-ADAMTS13, and Red Blood Cell Autoantibodies |
| title_full | Hematologic Chaos in Lupus Flare: A Case of Fulminant and Simultaneous Antiphospholipid, Anti-ADAMTS13, and Red Blood Cell Autoantibodies |
| title_fullStr | Hematologic Chaos in Lupus Flare: A Case of Fulminant and Simultaneous Antiphospholipid, Anti-ADAMTS13, and Red Blood Cell Autoantibodies |
| title_full_unstemmed | Hematologic Chaos in Lupus Flare: A Case of Fulminant and Simultaneous Antiphospholipid, Anti-ADAMTS13, and Red Blood Cell Autoantibodies |
| title_short | Hematologic Chaos in Lupus Flare: A Case of Fulminant and Simultaneous Antiphospholipid, Anti-ADAMTS13, and Red Blood Cell Autoantibodies |
| title_sort | hematologic chaos in lupus flare a case of fulminant and simultaneous antiphospholipid anti adamts13 and red blood cell autoantibodies |
| url | http://dx.doi.org/10.1155/2020/8812550 |
| work_keys_str_mv | AT jafaralmondhiry hematologicchaosinlupusflareacaseoffulminantandsimultaneousantiphospholipidantiadamts13andredbloodcellautoantibodies AT carolineychen hematologicchaosinlupusflareacaseoffulminantandsimultaneousantiphospholipidantiadamts13andredbloodcellautoantibodies AT michaelhrosove hematologicchaosinlupusflareacaseoffulminantandsimultaneousantiphospholipidantiadamts13andredbloodcellautoantibodies |