The impact of late liver allograft dysfunction on physical activity of liver transplant recipients
Introduction. Liver transplantation restores patients' physical and social life, and its quality. The prevalence of low physical activity in liver recipients is unknown as well as the impact of late liver allograft dysfunction on it. Liver transplantation enhances patient's return to the u...
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N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department
2021-12-01
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| Series: | Трансплантология (Москва) |
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| Online Access: | https://www.jtransplantologiya.ru/jour/article/view/612 |
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| author | Yu. O. Malinovskaya K. Yu. Kokina Ya. G. Moysyuk O. V. Sumtsova |
| author_facet | Yu. O. Malinovskaya K. Yu. Kokina Ya. G. Moysyuk O. V. Sumtsova |
| author_sort | Yu. O. Malinovskaya |
| collection | DOAJ |
| description | Introduction. Liver transplantation restores patients' physical and social life, and its quality. The prevalence of low physical activity in liver recipients is unknown as well as the impact of late liver allograft dysfunction on it. Liver transplantation enhances patient's return to the usual physical and social activity and improves the quality of life. However, the prevalence of low physical activity among liver recipients and the impact of the late allograft dysfunction on it, which is a risk factor for obesity and cardiovascular diseases, require studying.The aim of the study was to identify whether the late liver allograft dysfunction influences the physical activity of recipients.Material and methods. The study included 87 liver recipients. We measured anthropometric parameters, physical performance (SPPB, LFI, 6-min walk test), mean step count per day. Late liver allograft dysfunction was determined if elevated transaminases and/or cholestatic enzymes or hepatic failure have been diagnosed later than 3 months posttransplant. Activity trackers were provided to assess physical activity.Results. Median age was 54 years [45;61], 33% were men. The median follow-up period was 36 months [16;64]. The median of the average steps count was 5.9 [4.1;8.7] thousand per day. 60.5% of recipients were sedentary and low active, 24.4% were somewhat active, 15.1% were active. In cases of liver allograft dysfunction, the mean step count was significantly lower than in patients with normal liver function: 4.1 thousand [2.6;5.3] versus 6.8 thousand [4.2;9.4], p=0.003, despite no differences in the physical activity test results.Conclusion. In case of a late liver allograft dysfunction, the physical activity can decrease; 60.5% of liver recipients, in the absence of pathological restriction of movement, have a sedentary and low active lifestyle. Activity trackers may allow identifying patients who need additional check-up or physical training. |
| format | Article |
| id | doaj-art-b67b08ba6b1b455ca8b7ce72f6eab362 |
| institution | DOAJ |
| issn | 2074-0506 2542-0909 |
| language | English |
| publishDate | 2021-12-01 |
| publisher | N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department |
| record_format | Article |
| series | Трансплантология (Москва) |
| spelling | doaj-art-b67b08ba6b1b455ca8b7ce72f6eab3622025-08-20T02:55:45ZengN.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare DepartmentТрансплантология (Москва)2074-05062542-09092021-12-0113435636610.23873/2074-0506-2021-13-4-356-366494The impact of late liver allograft dysfunction on physical activity of liver transplant recipientsYu. O. Malinovskaya0K. Yu. Kokina1Ya. G. Moysyuk2O. V. Sumtsova3Moscow Regional Research and Clinical Institute n.a. M.F. VladimirskiyMoscow Regional Research and Clinical Institute n.a. M.F. VladimirskiyMoscow Regional Research and Clinical Institute n.a. M.F. VladimirskiyMoscow Regional Research and Clinical Institute n.a. M.F. VladimirskiyIntroduction. Liver transplantation restores patients' physical and social life, and its quality. The prevalence of low physical activity in liver recipients is unknown as well as the impact of late liver allograft dysfunction on it. Liver transplantation enhances patient's return to the usual physical and social activity and improves the quality of life. However, the prevalence of low physical activity among liver recipients and the impact of the late allograft dysfunction on it, which is a risk factor for obesity and cardiovascular diseases, require studying.The aim of the study was to identify whether the late liver allograft dysfunction influences the physical activity of recipients.Material and methods. The study included 87 liver recipients. We measured anthropometric parameters, physical performance (SPPB, LFI, 6-min walk test), mean step count per day. Late liver allograft dysfunction was determined if elevated transaminases and/or cholestatic enzymes or hepatic failure have been diagnosed later than 3 months posttransplant. Activity trackers were provided to assess physical activity.Results. Median age was 54 years [45;61], 33% were men. The median follow-up period was 36 months [16;64]. The median of the average steps count was 5.9 [4.1;8.7] thousand per day. 60.5% of recipients were sedentary and low active, 24.4% were somewhat active, 15.1% were active. In cases of liver allograft dysfunction, the mean step count was significantly lower than in patients with normal liver function: 4.1 thousand [2.6;5.3] versus 6.8 thousand [4.2;9.4], p=0.003, despite no differences in the physical activity test results.Conclusion. In case of a late liver allograft dysfunction, the physical activity can decrease; 60.5% of liver recipients, in the absence of pathological restriction of movement, have a sedentary and low active lifestyle. Activity trackers may allow identifying patients who need additional check-up or physical training.https://www.jtransplantologiya.ru/jour/article/view/612activity trackerwearable deviceliver transplantationobesitysedentary lifestyleliver recipientlong term transplant follow-up |
| spellingShingle | Yu. O. Malinovskaya K. Yu. Kokina Ya. G. Moysyuk O. V. Sumtsova The impact of late liver allograft dysfunction on physical activity of liver transplant recipients Трансплантология (Москва) activity tracker wearable device liver transplantation obesity sedentary lifestyle liver recipient long term transplant follow-up |
| title | The impact of late liver allograft dysfunction on physical activity of liver transplant recipients |
| title_full | The impact of late liver allograft dysfunction on physical activity of liver transplant recipients |
| title_fullStr | The impact of late liver allograft dysfunction on physical activity of liver transplant recipients |
| title_full_unstemmed | The impact of late liver allograft dysfunction on physical activity of liver transplant recipients |
| title_short | The impact of late liver allograft dysfunction on physical activity of liver transplant recipients |
| title_sort | impact of late liver allograft dysfunction on physical activity of liver transplant recipients |
| topic | activity tracker wearable device liver transplantation obesity sedentary lifestyle liver recipient long term transplant follow-up |
| url | https://www.jtransplantologiya.ru/jour/article/view/612 |
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