TLR4-dependent neuroinflammation mediates LPS-driven food-reward alterations during high-fat exposure

TLR4-dependent neuroinflammation mediates LPS-driven food-reward alterations during high-fat exposure

Abstract Background Obesity has become a global pandemic, marked by significant shifts in both the homeostatic and hedonic/reward aspects of food consumption. While the precise causes are still under investigation, recent studies have identified the role of gut microbes in dysregulating the reward s...

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Bibliographic Details
Main Authors: Sabrina J. P. Huwart, Clémence Fayt, Giuseppe Gangarossa, Serge Luquet, Patrice D. Cani, Amandine Everard
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Neuroinflammation
Subjects:
Food-reward
Obesity
Dopaminergic activity
Gut microbiota
Neuroinflammation
Lipopolysaccharides
Online Access:https://doi.org/10.1186/s12974-024-03297-z
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