The Role of Regulatory T Cells and TH17 Cells in Multiple Myeloma

The Role of Regulatory T Cells and TH17 Cells in Multiple Myeloma

The development of multiple myeloma (MM) involves a series of genetic alterations and changes in the bone marrow microenvironment, favoring the growth of the tumor and failure of local immune control. Quantitative and functional alterations in CD4+ and CD8+ T cells have been described in MM. The bal...

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Bibliographic Details
Main Authors: Walter M. T. Braga, Djordje Atanackovic, Gisele W. B. Colleoni
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2012/293479
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