INFLAMMATORY BOWEL DISEASE: CYTOCHEMICAL ACTIVITY OF INTRACELLULAR ENZYMES OF PERIPHERAL BLOOD NEUTROPHILS AND MONOCYTES IN DIAGNOSIS
Aim. To carry out literature analysis devoted to the studies of the importance of peripheral blood neutrophils and monocytes in the pathogenesis and diagnosis of inflammatory bowel diseases, namely Crohn's disease and ulcerative colitis. Blood neutrophils and monocytes, as the main components o...
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| Language: | Russian |
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Ministry of Healthcare of the Russian Federation. “Kuban State Medical University”
2017-09-01
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| Series: | Кубанский научный медицинский вестник |
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| Online Access: | https://ksma.elpub.ru/jour/article/view/800 |
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| author | V. A. ЕMELYANOVA A. A. DEMIDOV N. V. KOSTENKO E. N. CHERNYSHEVA |
| author_facet | V. A. ЕMELYANOVA A. A. DEMIDOV N. V. KOSTENKO E. N. CHERNYSHEVA |
| author_sort | V. A. ЕMELYANOVA |
| collection | DOAJ |
| description | Aim. To carry out literature analysis devoted to the studies of the importance of peripheral blood neutrophils and monocytes in the pathogenesis and diagnosis of inflammatory bowel diseases, namely Crohn's disease and ulcerative colitis. Blood neutrophils and monocytes, as the main components of the inflammatory infiltration of the intestinal wall, are the sources of inflammatory mediators, pro-inflammatory cytokines, involved in the mechanisms of the mucous membrane destruction. Change of these blood cells intracellular enzymes activity using cytochemical methods can indicate the activity of the systemic inflammatory process, which reflects the activity of this process in the intestinal wall, and make possible prognosis of the disease course.Conclusion. Further study of the dynamics of the functional activity of blood neutrophils and monocytes will make possible design of diagnostic algorithms for inflammatory bowel diseases and assess the effectiveness of the therapy. |
| format | Article |
| id | doaj-art-b66615e3531f4ae09dafecdbb70e32cc |
| institution | Kabale University |
| issn | 1608-6228 2541-9544 |
| language | Russian |
| publishDate | 2017-09-01 |
| publisher | Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” |
| record_format | Article |
| series | Кубанский научный медицинский вестник |
| spelling | doaj-art-b66615e3531f4ae09dafecdbb70e32cc2025-08-20T03:57:12ZrusMinistry of Healthcare of the Russian Federation. “Kuban State Medical University”Кубанский научный медицинский вестник1608-62282541-95442017-09-010313714110.25207/1608-6228-2017-24-3-137-141773INFLAMMATORY BOWEL DISEASE: CYTOCHEMICAL ACTIVITY OF INTRACELLULAR ENZYMES OF PERIPHERAL BLOOD NEUTROPHILS AND MONOCYTES IN DIAGNOSISV. A. ЕMELYANOVA0A. A. DEMIDOV1N. V. KOSTENKO2E. N. CHERNYSHEVA3Astrakhan State Medical UniversityAstrakhan State Medical UniversityAstrakhan State Medical UniversityAstrakhan State Medical UniversityAim. To carry out literature analysis devoted to the studies of the importance of peripheral blood neutrophils and monocytes in the pathogenesis and diagnosis of inflammatory bowel diseases, namely Crohn's disease and ulcerative colitis. Blood neutrophils and monocytes, as the main components of the inflammatory infiltration of the intestinal wall, are the sources of inflammatory mediators, pro-inflammatory cytokines, involved in the mechanisms of the mucous membrane destruction. Change of these blood cells intracellular enzymes activity using cytochemical methods can indicate the activity of the systemic inflammatory process, which reflects the activity of this process in the intestinal wall, and make possible prognosis of the disease course.Conclusion. Further study of the dynamics of the functional activity of blood neutrophils and monocytes will make possible design of diagnostic algorithms for inflammatory bowel diseases and assess the effectiveness of the therapy.https://ksma.elpub.ru/jour/article/view/800inflammatory bowel diseasecrohn's diseaseulcerative colitisneutrophilsmonocytes |
| spellingShingle | V. A. ЕMELYANOVA A. A. DEMIDOV N. V. KOSTENKO E. N. CHERNYSHEVA INFLAMMATORY BOWEL DISEASE: CYTOCHEMICAL ACTIVITY OF INTRACELLULAR ENZYMES OF PERIPHERAL BLOOD NEUTROPHILS AND MONOCYTES IN DIAGNOSIS Кубанский научный медицинский вестник inflammatory bowel disease crohn's disease ulcerative colitis neutrophils monocytes |
| title | INFLAMMATORY BOWEL DISEASE: CYTOCHEMICAL ACTIVITY OF INTRACELLULAR ENZYMES OF PERIPHERAL BLOOD NEUTROPHILS AND MONOCYTES IN DIAGNOSIS |
| title_full | INFLAMMATORY BOWEL DISEASE: CYTOCHEMICAL ACTIVITY OF INTRACELLULAR ENZYMES OF PERIPHERAL BLOOD NEUTROPHILS AND MONOCYTES IN DIAGNOSIS |
| title_fullStr | INFLAMMATORY BOWEL DISEASE: CYTOCHEMICAL ACTIVITY OF INTRACELLULAR ENZYMES OF PERIPHERAL BLOOD NEUTROPHILS AND MONOCYTES IN DIAGNOSIS |
| title_full_unstemmed | INFLAMMATORY BOWEL DISEASE: CYTOCHEMICAL ACTIVITY OF INTRACELLULAR ENZYMES OF PERIPHERAL BLOOD NEUTROPHILS AND MONOCYTES IN DIAGNOSIS |
| title_short | INFLAMMATORY BOWEL DISEASE: CYTOCHEMICAL ACTIVITY OF INTRACELLULAR ENZYMES OF PERIPHERAL BLOOD NEUTROPHILS AND MONOCYTES IN DIAGNOSIS |
| title_sort | inflammatory bowel disease cytochemical activity of intracellular enzymes of peripheral blood neutrophils and monocytes in diagnosis |
| topic | inflammatory bowel disease crohn's disease ulcerative colitis neutrophils monocytes |
| url | https://ksma.elpub.ru/jour/article/view/800 |
| work_keys_str_mv | AT vaemelyanova inflammatoryboweldiseasecytochemicalactivityofintracellularenzymesofperipheralbloodneutrophilsandmonocytesindiagnosis AT aademidov inflammatoryboweldiseasecytochemicalactivityofintracellularenzymesofperipheralbloodneutrophilsandmonocytesindiagnosis AT nvkostenko inflammatoryboweldiseasecytochemicalactivityofintracellularenzymesofperipheralbloodneutrophilsandmonocytesindiagnosis AT enchernysheva inflammatoryboweldiseasecytochemicalactivityofintracellularenzymesofperipheralbloodneutrophilsandmonocytesindiagnosis |