Exploring the impact of stimulant medications on weight in children with attention deficit hyperactivity disorder in Dubai, United Arab Emirates

ObjectiveAttention deficit hyperactivity disorder (ADHD), prevalent in 5% of children worldwide, impacts academic performance and often coexists with psychiatric disorders. Psychostimulant medications are primary treatments for ADHD, enhancing dopamine to reduce symptoms. However, dopamine increase...

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Main Authors: Faten Al Eid, Ammar Albanna, Jessie Joseph, Sami Talo, Lakshmanan Jeyaseelan, Meshal A. Sultan
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Psychiatry
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Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1392846/full
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author Faten Al Eid
Faten Al Eid
Ammar Albanna
Ammar Albanna
Jessie Joseph
Sami Talo
Lakshmanan Jeyaseelan
Meshal A. Sultan
author_facet Faten Al Eid
Faten Al Eid
Ammar Albanna
Ammar Albanna
Jessie Joseph
Sami Talo
Lakshmanan Jeyaseelan
Meshal A. Sultan
author_sort Faten Al Eid
collection DOAJ
description ObjectiveAttention deficit hyperactivity disorder (ADHD), prevalent in 5% of children worldwide, impacts academic performance and often coexists with psychiatric disorders. Psychostimulant medications are primary treatments for ADHD, enhancing dopamine to reduce symptoms. However, dopamine increase may cause appetite loss. This pioneering study in the United Arab Emirates (UAE) explores psychostimulant effects on weight in children diagnosed with ADHD, aiming to uncover unique regional characteristics and contributing factors to weight changes.MethodsThis retrospective cohort study assessed data from electronic medical records from 2017 to 2022, aiming to assess the impact of psychostimulants on weight in children aged 6–18 years. Inclusion criteria covered psychostimulant-treated and untreated patients with ADHD. Statistical analysis, involving longitudinal data methods aimed to demonstrate significant weight differences.ResultsData from 107 pediatric patients diagnosed with ADHD were analyzed, with 86 meeting inclusion criteria. Most patients were male (80.2%). ADHD presentations varied, and methylphenidate immediate release was the most prescribed stimulant medication. Patients experienced initial weight loss followed by overall gain over 12 months. Coexisting conditions, maternal factors, family history, and correlations with autism spectrum disorder were explored.ConclusionThis study provides valuable insights into the effects of psychostimulant medications on the weight of children and adolescents diagnosed with ADHD in the UAE. It suggests avenues for future research, emphasizing extended follow-ups to understand long-term psychostimulant effects, nuanced examinations of age and gender, and exploring interactions with comorbidities. Despite limitations, the research provides insights into ADHD medication effects, guiding personalized treatment approaches for pediatric populations.
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spelling doaj-art-b6544bed81ce4e709804a4eaf121c5c22025-08-20T01:47:37ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402024-10-011510.3389/fpsyt.2024.13928461392846Exploring the impact of stimulant medications on weight in children with attention deficit hyperactivity disorder in Dubai, United Arab EmiratesFaten Al Eid0Faten Al Eid1Ammar Albanna2Ammar Albanna3Jessie Joseph4Sami Talo5Lakshmanan Jeyaseelan6Meshal A. Sultan7College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Health, Dubai, United Arab EmiratesMental Health Centre of Excellence, Al Jalila Children’s Specialty Hospital, Dubai Health, Dubai, United Arab EmiratesCollege of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Health, Dubai, United Arab EmiratesAl Amal Psychiatric Hospital, Emirates Health Services, Dubai, United Arab EmiratesCollege of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Health, Dubai, United Arab EmiratesCollege of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Health, Dubai, United Arab EmiratesCollege of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Health, Dubai, United Arab EmiratesCollege of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Health, Dubai, United Arab EmiratesObjectiveAttention deficit hyperactivity disorder (ADHD), prevalent in 5% of children worldwide, impacts academic performance and often coexists with psychiatric disorders. Psychostimulant medications are primary treatments for ADHD, enhancing dopamine to reduce symptoms. However, dopamine increase may cause appetite loss. This pioneering study in the United Arab Emirates (UAE) explores psychostimulant effects on weight in children diagnosed with ADHD, aiming to uncover unique regional characteristics and contributing factors to weight changes.MethodsThis retrospective cohort study assessed data from electronic medical records from 2017 to 2022, aiming to assess the impact of psychostimulants on weight in children aged 6–18 years. Inclusion criteria covered psychostimulant-treated and untreated patients with ADHD. Statistical analysis, involving longitudinal data methods aimed to demonstrate significant weight differences.ResultsData from 107 pediatric patients diagnosed with ADHD were analyzed, with 86 meeting inclusion criteria. Most patients were male (80.2%). ADHD presentations varied, and methylphenidate immediate release was the most prescribed stimulant medication. Patients experienced initial weight loss followed by overall gain over 12 months. Coexisting conditions, maternal factors, family history, and correlations with autism spectrum disorder were explored.ConclusionThis study provides valuable insights into the effects of psychostimulant medications on the weight of children and adolescents diagnosed with ADHD in the UAE. It suggests avenues for future research, emphasizing extended follow-ups to understand long-term psychostimulant effects, nuanced examinations of age and gender, and exploring interactions with comorbidities. Despite limitations, the research provides insights into ADHD medication effects, guiding personalized treatment approaches for pediatric populations.https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1392846/fullpsychostimulantsweightchildrenadolescentsattention deficit hyperactivity disorder (ADHD)
spellingShingle Faten Al Eid
Faten Al Eid
Ammar Albanna
Ammar Albanna
Jessie Joseph
Sami Talo
Lakshmanan Jeyaseelan
Meshal A. Sultan
Exploring the impact of stimulant medications on weight in children with attention deficit hyperactivity disorder in Dubai, United Arab Emirates
Frontiers in Psychiatry
psychostimulants
weight
children
adolescents
attention deficit hyperactivity disorder (ADHD)
title Exploring the impact of stimulant medications on weight in children with attention deficit hyperactivity disorder in Dubai, United Arab Emirates
title_full Exploring the impact of stimulant medications on weight in children with attention deficit hyperactivity disorder in Dubai, United Arab Emirates
title_fullStr Exploring the impact of stimulant medications on weight in children with attention deficit hyperactivity disorder in Dubai, United Arab Emirates
title_full_unstemmed Exploring the impact of stimulant medications on weight in children with attention deficit hyperactivity disorder in Dubai, United Arab Emirates
title_short Exploring the impact of stimulant medications on weight in children with attention deficit hyperactivity disorder in Dubai, United Arab Emirates
title_sort exploring the impact of stimulant medications on weight in children with attention deficit hyperactivity disorder in dubai united arab emirates
topic psychostimulants
weight
children
adolescents
attention deficit hyperactivity disorder (ADHD)
url https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1392846/full
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