PROBLEMATIC ISSUES OF HIGHLY ACTIVE ANTIRETROVIRAL THERAPY IN HIV-INFECTED PATIENTS WITH ENDOGENOUS MENTAL DISORDERS
The aim: to identify changes in mental status due to receive HAART and comprehensive assessment of the biological, behavioral and social factors in adherence to treatment in HIV-infected patients with endogenous mental disorders. Material: The study involved 53 patients with HIV infection and schizo...
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| Format: | Article |
| Language: | Russian |
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Journal Infectology
2017-04-01
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| Series: | Журнал инфектологии |
| Subjects: | |
| Online Access: | https://journal.niidi.ru/jofin/article/view/564 |
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| author | N. G. Neznanov N. B. Khalezova A. A. Khobeish N. P Petrov |
| author_facet | N. G. Neznanov N. B. Khalezova A. A. Khobeish N. P Petrov |
| author_sort | N. G. Neznanov |
| collection | DOAJ |
| description | The aim: to identify changes in mental status due to receive HAART and comprehensive assessment of the biological, behavioral and social factors in adherence to treatment in HIV-infected patients with endogenous mental disorders. Material: The study involved 53 patients with HIV infection and schizophrenia / affective spectrum comorbidity. Results: In the tolerability and adherence to ARV therapy affects not only the neurobiological vulnerability, but also a change in the mental state and condition of the patient social life. After the start of ART mental state of patients with endogenous mental disorders often deteriorates. Depending on their degree of penetration into the central nervous system were observed pronounced effect of ART on the structure of psychopathological symptoms and the course of mental illness in general. |
| format | Article |
| id | doaj-art-b64ef96a330e44ecb277662805203e8f |
| institution | Kabale University |
| issn | 2072-6732 |
| language | Russian |
| publishDate | 2017-04-01 |
| publisher | Journal Infectology |
| record_format | Article |
| series | Журнал инфектологии |
| spelling | doaj-art-b64ef96a330e44ecb277662805203e8f2025-08-20T03:44:23ZrusJournal InfectologyЖурнал инфектологии2072-67322017-04-0191677510.22625/2072-6732-2017-9-1-67-75534PROBLEMATIC ISSUES OF HIGHLY ACTIVE ANTIRETROVIRAL THERAPY IN HIV-INFECTED PATIENTS WITH ENDOGENOUS MENTAL DISORDERSN. G. Neznanov0N. B. Khalezova1A. A. Khobeish2N. P Petrov3Saint-Petersburg Science Research Neuropsychiatric Institute named after V.M. Behterev; First Saint-Petersburg State Medical University named after academician I.P. PavlovFirst Saint-Petersburg State Medical University named after academician I.P. Pavlov; Saint-Petersburg Center for the Prevention and Control of AIDS and Infectious DiseasesFirst Saint-Petersburg State Medical University named after academician I.P. PavlovFirst Saint-Petersburg State Medical University named after academician I.P. PavlovThe aim: to identify changes in mental status due to receive HAART and comprehensive assessment of the biological, behavioral and social factors in adherence to treatment in HIV-infected patients with endogenous mental disorders. Material: The study involved 53 patients with HIV infection and schizophrenia / affective spectrum comorbidity. Results: In the tolerability and adherence to ARV therapy affects not only the neurobiological vulnerability, but also a change in the mental state and condition of the patient social life. After the start of ART mental state of patients with endogenous mental disorders often deteriorates. Depending on their degree of penetration into the central nervous system were observed pronounced effect of ART on the structure of psychopathological symptoms and the course of mental illness in general.https://journal.niidi.ru/jofin/article/view/564hivschizophrenia spectrum disordersaffective disordershighly active antiretroviral therapy |
| spellingShingle | N. G. Neznanov N. B. Khalezova A. A. Khobeish N. P Petrov PROBLEMATIC ISSUES OF HIGHLY ACTIVE ANTIRETROVIRAL THERAPY IN HIV-INFECTED PATIENTS WITH ENDOGENOUS MENTAL DISORDERS Журнал инфектологии hiv schizophrenia spectrum disorders affective disorders highly active antiretroviral therapy |
| title | PROBLEMATIC ISSUES OF HIGHLY ACTIVE ANTIRETROVIRAL THERAPY IN HIV-INFECTED PATIENTS WITH ENDOGENOUS MENTAL DISORDERS |
| title_full | PROBLEMATIC ISSUES OF HIGHLY ACTIVE ANTIRETROVIRAL THERAPY IN HIV-INFECTED PATIENTS WITH ENDOGENOUS MENTAL DISORDERS |
| title_fullStr | PROBLEMATIC ISSUES OF HIGHLY ACTIVE ANTIRETROVIRAL THERAPY IN HIV-INFECTED PATIENTS WITH ENDOGENOUS MENTAL DISORDERS |
| title_full_unstemmed | PROBLEMATIC ISSUES OF HIGHLY ACTIVE ANTIRETROVIRAL THERAPY IN HIV-INFECTED PATIENTS WITH ENDOGENOUS MENTAL DISORDERS |
| title_short | PROBLEMATIC ISSUES OF HIGHLY ACTIVE ANTIRETROVIRAL THERAPY IN HIV-INFECTED PATIENTS WITH ENDOGENOUS MENTAL DISORDERS |
| title_sort | problematic issues of highly active antiretroviral therapy in hiv infected patients with endogenous mental disorders |
| topic | hiv schizophrenia spectrum disorders affective disorders highly active antiretroviral therapy |
| url | https://journal.niidi.ru/jofin/article/view/564 |
| work_keys_str_mv | AT ngneznanov problematicissuesofhighlyactiveantiretroviraltherapyinhivinfectedpatientswithendogenousmentaldisorders AT nbkhalezova problematicissuesofhighlyactiveantiretroviraltherapyinhivinfectedpatientswithendogenousmentaldisorders AT aakhobeish problematicissuesofhighlyactiveantiretroviraltherapyinhivinfectedpatientswithendogenousmentaldisorders AT nppetrov problematicissuesofhighlyactiveantiretroviraltherapyinhivinfectedpatientswithendogenousmentaldisorders |