Improving Geldanamycin Production in <i>Streptomyces geldanamycininus</i> Through UV Mutagenesis of Protoplast

Improving Geldanamycin Production in <i>Streptomyces geldanamycininus</i> Through UV Mutagenesis of Protoplast

Geldanamycin, a benzoquinone ansa antibiotic, has been extensively applied in medical, agricultural, and health research areas due to its antitumor, antifungal, herbicidal, and antiradiation effects. In this study, an improvement of geldanamycin production by <i>Streptomyces geldanamycininus&l...

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Bibliographic Details
Main Authors: Yuan Yuan, Lu Yang, Zhikai Fang, Haimin Chen, Fei Sun, Hong Jiang, Jian Zhou
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Microorganisms
Subjects:
whole-genome sequencing
transcriptome sequencing
protoplast mutagenesis
UV mutagenesis
geldanamycin
Online Access:https://www.mdpi.com/2076-2607/13/1/186
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