Erianin inhibits cell migration and induces apoptosis by inhibiting VEGF-α/PI3K/AKT signaling pathway in malignant melanoma

Erianin inhibits cell migration and induces apoptosis by inhibiting VEGF-α/PI3K/AKT signaling pathway in malignant melanoma

Abstract Erianin, extracted from Dendrobium chrysotoxum Lindl, has shown significant antitumour activity in various cancers, including bladder, cervical, and nasopharyngeal carcinoma. This study explores Erianin’s impact on melanoma, a prevalent intraocular malignancy in adults, emphasizing cell gro...

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Bibliographic Details
Main Authors: Hao Sun, Gaolei Wang, Cong Ren, Xi Zhang, Ping Zhao, Bin Guo
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Erianin
Melanoma
VEGF-α
VEGF receptor 2
PI3K/AKT/mTOR signalling pathway
Online Access:https://doi.org/10.1038/s41598-025-99383-0
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