Impaired Glucose Metabolism Is Associated with Visit-to-Visit Blood Pressure Variability in Participants without Cardiovascular Disease
We evaluated data from 10,088 participants without cardiovascular disease (CVD) who underwent 75 g oral glucose tolerance tests and had more than four visits during the first 5 years following the test to investigate the association between impaired glucose metabolism and visit-to-visit blood pressu...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2018-01-01
|
| Series: | International Journal of Hypertension |
| Online Access: | http://dx.doi.org/10.1155/2018/5126270 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832560896016121856 |
|---|---|
| author | Nobuo Sasaki Ryoji Ozono Saeko Fujiwara Ryo Maeda Yasuki Kihara |
| author_facet | Nobuo Sasaki Ryoji Ozono Saeko Fujiwara Ryo Maeda Yasuki Kihara |
| author_sort | Nobuo Sasaki |
| collection | DOAJ |
| description | We evaluated data from 10,088 participants without cardiovascular disease (CVD) who underwent 75 g oral glucose tolerance tests and had more than four visits during the first 5 years following the test to investigate the association between impaired glucose metabolism and visit-to-visit blood pressure (BP) variability. Participants were classified into groups of normal glucose tolerance (NGT), impaired fasting glucose (IFG), impaired glucose tolerance (IGT), and diabetes. Visit-to-visit BP variability was estimated for each individual using standard deviation (SD) and coefficients of variation (CV, defined as SD/mean). SDs and CVs of systolic BP (SBP) values were divided into quartiles. The samples falling in the highest quartile were considered as having high SD/CV. The adjusted odds ratio (OR) for high SD of SBP in the IFG (OR, 1.39; P<0.003), IGT (OR, 1.26; P<0.001), and diabetes (OR, 1.54; P<0.001) groups was significantly higher than that for high SD of SBP in the NGT group. Similarly, the OR for high CV of SBP in the IGT and diabetes groups was significantly higher than that for high CV of SBP in the NGT group. In participants without CVD, impaired glucose metabolism may modulate visit-to-visit BP variability. |
| format | Article |
| id | doaj-art-b630d25569934148bc6a317b0ea0cc45 |
| institution | Kabale University |
| issn | 2090-0384 2090-0392 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Hypertension |
| spelling | doaj-art-b630d25569934148bc6a317b0ea0cc452025-02-03T01:26:30ZengWileyInternational Journal of Hypertension2090-03842090-03922018-01-01201810.1155/2018/51262705126270Impaired Glucose Metabolism Is Associated with Visit-to-Visit Blood Pressure Variability in Participants without Cardiovascular DiseaseNobuo Sasaki0Ryoji Ozono1Saeko Fujiwara2Ryo Maeda3Yasuki Kihara4Health Management and Promotion Center, Hiroshima Atomic Bomb Casualty Council, Hiroshima, JapanDepartment of General Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, JapanHealth Management and Promotion Center, Hiroshima Atomic Bomb Casualty Council, Hiroshima, JapanHealth Management and Promotion Center, Hiroshima Atomic Bomb Casualty Council, Hiroshima, JapanDepartment of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, JapanWe evaluated data from 10,088 participants without cardiovascular disease (CVD) who underwent 75 g oral glucose tolerance tests and had more than four visits during the first 5 years following the test to investigate the association between impaired glucose metabolism and visit-to-visit blood pressure (BP) variability. Participants were classified into groups of normal glucose tolerance (NGT), impaired fasting glucose (IFG), impaired glucose tolerance (IGT), and diabetes. Visit-to-visit BP variability was estimated for each individual using standard deviation (SD) and coefficients of variation (CV, defined as SD/mean). SDs and CVs of systolic BP (SBP) values were divided into quartiles. The samples falling in the highest quartile were considered as having high SD/CV. The adjusted odds ratio (OR) for high SD of SBP in the IFG (OR, 1.39; P<0.003), IGT (OR, 1.26; P<0.001), and diabetes (OR, 1.54; P<0.001) groups was significantly higher than that for high SD of SBP in the NGT group. Similarly, the OR for high CV of SBP in the IGT and diabetes groups was significantly higher than that for high CV of SBP in the NGT group. In participants without CVD, impaired glucose metabolism may modulate visit-to-visit BP variability.http://dx.doi.org/10.1155/2018/5126270 |
| spellingShingle | Nobuo Sasaki Ryoji Ozono Saeko Fujiwara Ryo Maeda Yasuki Kihara Impaired Glucose Metabolism Is Associated with Visit-to-Visit Blood Pressure Variability in Participants without Cardiovascular Disease International Journal of Hypertension |
| title | Impaired Glucose Metabolism Is Associated with Visit-to-Visit Blood Pressure Variability in Participants without Cardiovascular Disease |
| title_full | Impaired Glucose Metabolism Is Associated with Visit-to-Visit Blood Pressure Variability in Participants without Cardiovascular Disease |
| title_fullStr | Impaired Glucose Metabolism Is Associated with Visit-to-Visit Blood Pressure Variability in Participants without Cardiovascular Disease |
| title_full_unstemmed | Impaired Glucose Metabolism Is Associated with Visit-to-Visit Blood Pressure Variability in Participants without Cardiovascular Disease |
| title_short | Impaired Glucose Metabolism Is Associated with Visit-to-Visit Blood Pressure Variability in Participants without Cardiovascular Disease |
| title_sort | impaired glucose metabolism is associated with visit to visit blood pressure variability in participants without cardiovascular disease |
| url | http://dx.doi.org/10.1155/2018/5126270 |
| work_keys_str_mv | AT nobuosasaki impairedglucosemetabolismisassociatedwithvisittovisitbloodpressurevariabilityinparticipantswithoutcardiovasculardisease AT ryojiozono impairedglucosemetabolismisassociatedwithvisittovisitbloodpressurevariabilityinparticipantswithoutcardiovasculardisease AT saekofujiwara impairedglucosemetabolismisassociatedwithvisittovisitbloodpressurevariabilityinparticipantswithoutcardiovasculardisease AT ryomaeda impairedglucosemetabolismisassociatedwithvisittovisitbloodpressurevariabilityinparticipantswithoutcardiovasculardisease AT yasukikihara impairedglucosemetabolismisassociatedwithvisittovisitbloodpressurevariabilityinparticipantswithoutcardiovasculardisease |