Baseline predictors for 28-day COVID-19 severity and mortality among hospitalized patients: results from the IMPACC study

Baseline predictors for 28-day COVID-19 severity and mortality among hospitalized patients: results from the IMPACC study

IntroductionThe coronavirus disease 2019 (COVID-19) pandemic threatened public health and placed a significant burden on medical resources. The Immunophenotyping Assessment in a COVID-19 Cohort (IMPACC) study collected clinical, demographic, blood cytometry, serum receptor-binding domain (RBD) antib...

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Main Authors: Jintong Hou, Benjamin Haslund-Gourley, Joann Diray-Arce, Annmarie Hoch, Nadine Rouphael, Patrice M. Becker, Alison D. Augustine, Al Ozonoff, Leying Guan, Steven H. Kleinstein, Bjoern Peters, Elaine Reed, Matt Altman, Charles R. Langelier, Holden Maecker, Seunghee Kim, Ruth R. Montgomery, Florian Krammer, Michael Wilson, Walter Eckalbar, Steven E. Bosinger, Ofer Levy, Hanno Steen, Lindsey B. Rosen, Lindsey R. Baden, Esther Melamed, Lauren I. R. Ehrlich, Grace A. McComsey, Rafick P. Sekaly, Joanna Schaenman, Albert C. Shaw, David A. Hafler, David B. Corry, Farrah Kheradmand, Mark A. Atkinson, Scott C. Brakenridge, Nelson I. Agudelo Higuita, Jordan P. Metcalf, Catherine L. Hough, William B. Messer, Bali Pulendran, Kari C. Nadeau, Mark M. Davis, Ana Fernandez Sesma, Viviana Simon, Monica Kraft, Chris Bime, Carolyn S. Calfee, David J. Erle, IMPACC Network, Lucy F. Robinson, Charles B. Cairns, Elias K. Haddad, Mary Ann Comunale
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Medicine
Subjects:
COVID-19
severity
mortality
machine learning
SpO2/FiO2
TNFRSF11B
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1604388/full
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