Role of polymorphic variants of DNA repair genes XRCC7 and XPD toward susceptibility of systemic lupus erythematosus and rheumatoid arthritis: a case control study

Role of polymorphic variants of DNA repair genes XRCC7 and XPD toward susceptibility of systemic lupus erythematosus and rheumatoid arthritis: a case control study

Abstract Background DNA damage is believed to be involved in the development of systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). The X-ray repair cross-complementation group (XRCC7) and Xeroderma pigmentosum group D (XPD) proteins play critical roles in DNA repair. This study invest...

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Bibliographic Details
Main Authors: Mohannad Fawzy Mustafa, Engy Mohammad El Khateeb, Tarek Gamal Eldein Megahed, Rania Soliman Hamza, Hend Hamed Tamim
Format: Article
Language:English
Published: SpringerOpen 2025-07-01
Series:Egyptian Journal of Medical Human Genetics
Subjects:
SLE
RA
XRCC7
XPD
ARMS
RFLP
Online Access:https://doi.org/10.1186/s43042-025-00760-1
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