Effect of neurokinin B and dynorphin A on kisspeptin-10 secretion from the anterior pituitary cells of pubescent ewes in vitro
Neurokinin B (NKB), dynorphin A (Dyn A) and kisspeptin (KiSS) are key agents that participate in the neuroendocrine regulation of the development and functioning of the reproductive system. While the role of KiSS is better understood, the functions of NKB and Dyn A at the pituitary level have not be...
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| Format: | Article |
| Language: | English |
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2025-05-01
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| Series: | Journal of Veterinary Research |
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| Online Access: | https://doi.org/10.2478/jvetres-2025-0026 |
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| author | Szysiak Natalia Kosior-Korzecka Urszula Greguła-Kania Monika Patkowski Krzysztof Fila Mateusz Junkuszew Andrzej |
| author_facet | Szysiak Natalia Kosior-Korzecka Urszula Greguła-Kania Monika Patkowski Krzysztof Fila Mateusz Junkuszew Andrzej |
| author_sort | Szysiak Natalia |
| collection | DOAJ |
| description | Neurokinin B (NKB), dynorphin A (Dyn A) and kisspeptin (KiSS) are key agents that participate in the neuroendocrine regulation of the development and functioning of the reproductive system. While the role of KiSS is better understood, the functions of NKB and Dyn A at the pituitary level have not been elucidated. The objective of our study was to analyse their direct effect on kisspeptin-10 (KiSS-10) secretion by anterior pituitary cells isolated from pubescent ewes. |
| format | Article |
| id | doaj-art-b6252a291d044a52be0e82e41299ce35 |
| institution | OA Journals |
| issn | 2450-8608 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Journal of Veterinary Research |
| spelling | doaj-art-b6252a291d044a52be0e82e41299ce352025-08-20T02:38:15ZengSciendoJournal of Veterinary Research2450-86082025-05-0169229930410.2478/jvetres-2025-0026Effect of neurokinin B and dynorphin A on kisspeptin-10 secretion from the anterior pituitary cells of pubescent ewes in vitroSzysiak Natalia0Kosior-Korzecka Urszula1Greguła-Kania Monika2Patkowski Krzysztof3Fila Mateusz4Junkuszew Andrzej51Sub-Department of Pathophysiology, Department of Preclinical Veterinary Sciences, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, 20-033Lublin, Poland1Sub-Department of Pathophysiology, Department of Preclinical Veterinary Sciences, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, 20-033Lublin, Poland2Department of Animal Breeding and Agricultural Advisory, Faculty of Animal Sciences and Bioeconomy, University of Life Sciences in Lublin, 20-950, Lublin, Poland2Department of Animal Breeding and Agricultural Advisory, Faculty of Animal Sciences and Bioeconomy, University of Life Sciences in Lublin, 20-950, Lublin, Poland1Sub-Department of Pathophysiology, Department of Preclinical Veterinary Sciences, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, 20-033Lublin, Poland2Department of Animal Breeding and Agricultural Advisory, Faculty of Animal Sciences and Bioeconomy, University of Life Sciences in Lublin, 20-950, Lublin, PolandNeurokinin B (NKB), dynorphin A (Dyn A) and kisspeptin (KiSS) are key agents that participate in the neuroendocrine regulation of the development and functioning of the reproductive system. While the role of KiSS is better understood, the functions of NKB and Dyn A at the pituitary level have not been elucidated. The objective of our study was to analyse their direct effect on kisspeptin-10 (KiSS-10) secretion by anterior pituitary cells isolated from pubescent ewes.https://doi.org/10.2478/jvetres-2025-0026neurokinin bdynorphin akisspeptinpituitarypuberty |
| spellingShingle | Szysiak Natalia Kosior-Korzecka Urszula Greguła-Kania Monika Patkowski Krzysztof Fila Mateusz Junkuszew Andrzej Effect of neurokinin B and dynorphin A on kisspeptin-10 secretion from the anterior pituitary cells of pubescent ewes in vitro Journal of Veterinary Research neurokinin b dynorphin a kisspeptin pituitary puberty |
| title | Effect of neurokinin B and dynorphin A on kisspeptin-10 secretion from the anterior pituitary cells of pubescent ewes in vitro |
| title_full | Effect of neurokinin B and dynorphin A on kisspeptin-10 secretion from the anterior pituitary cells of pubescent ewes in vitro |
| title_fullStr | Effect of neurokinin B and dynorphin A on kisspeptin-10 secretion from the anterior pituitary cells of pubescent ewes in vitro |
| title_full_unstemmed | Effect of neurokinin B and dynorphin A on kisspeptin-10 secretion from the anterior pituitary cells of pubescent ewes in vitro |
| title_short | Effect of neurokinin B and dynorphin A on kisspeptin-10 secretion from the anterior pituitary cells of pubescent ewes in vitro |
| title_sort | effect of neurokinin b and dynorphin a on kisspeptin 10 secretion from the anterior pituitary cells of pubescent ewes in vitro |
| topic | neurokinin b dynorphin a kisspeptin pituitary puberty |
| url | https://doi.org/10.2478/jvetres-2025-0026 |
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