Multi-omics analysis identified macrophages as key contributors to sex-related differences in ulcerative colitis

BackgroundUlcerative colitis (UC) has a complex etiology, and whether there are sex-related differences in its molecular mechanisms remains unclear. This study employed multi-omics analysis to explore sex-based differences in UC, aiming to provide support for personalized treatment.MethodsThe GSE368...

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Bibliographic Details
Main Authors:	Xiaojie Fang, Jiahao Yang, Liu Yang, Yiyou Lin, Yanyan Li, Xin Yin, Xiaobing Dou, Chenyun Miao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Series:	Frontiers in Immunology
Subjects:	inflammatory bowel disease sex-specific differences ulcerative colitis RPS4Y1 gene transcriptomics metabolomics
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1569271/full
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Multi-omics analysis identified macrophages as key contributors to sex-related differences in ulcerative colitis

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