Multifunctional RNA-binding proteins influence mRNA abundance and translational efficiency of distinct sets of target genes.
RNA-binding proteins (RBPs) can regulate more than a single aspect of RNA metabolism. We searched for such previously undiscovered multifunctionality within a set of 143 RBPs, by defining the predictive value of RBP abundance for the transcription and translation levels of known RBP target genes acr...
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| Main Authors: | Valentin Schneider-Lunitz, Jorge Ruiz-Orera, Norbert Hubner, Sebastiaan van Heesch |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2021-12-01
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| Series: | PLoS Computational Biology |
| Online Access: | https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1009658&type=printable |
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