Abdominal Pain as the Initial and Sole Clinical Presenting Feature of Systemic Lupus Erythematosus
Classically, a diagnosis of systemic lupus erythematosus (SLE) is dependent on renal, rheumatological, cutaneous and neurological target organ damage with supporting serological markers. A previously healthy 26-year-old Japanese woman whose only manifestation of otherwise occult SLE was severe abdom...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2003-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/2003/768184 |
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| author | Henry V Chung Alnoor Ramji Jennifer E Davis Sylvia Chang Graham D Reid Baljinder Salh Hugh J Freeman Eric M Yoshida |
| author_facet | Henry V Chung Alnoor Ramji Jennifer E Davis Sylvia Chang Graham D Reid Baljinder Salh Hugh J Freeman Eric M Yoshida |
| author_sort | Henry V Chung |
| collection | DOAJ |
| description | Classically, a diagnosis of systemic lupus erythematosus (SLE) is dependent on renal, rheumatological, cutaneous and neurological target organ damage with supporting serological markers. A previously healthy 26-year-old Japanese woman whose only manifestation of otherwise occult SLE was severe abdominal pain is reported. A computed tomographic scan of the abdomen revealed thickened loops of small bowel, endoscopic findings were nonspecific and jejunal biopsy revealed a nonspecific enteritis. Laboratory studies revealed lymphopenia, hypocomplementemia, a positive antinuclear antibody, a weakly positive anti-Smith and a strongly positive anti-double stranded DNA. There was a prompt symptomatic recovery with immunosuppressive therapy. The authors’ experiences, and a review of the literature suggest that a diagnosis of SLE should be considered in young Asian women who present with significant but clinically enigmatic gastrointestinal illness. |
| format | Article |
| id | doaj-art-b613f921cef24dd29a92813dd8b2ea4c |
| institution | DOAJ |
| issn | 0835-7900 |
| language | English |
| publishDate | 2003-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-b613f921cef24dd29a92813dd8b2ea4c2025-08-20T03:20:56ZengWileyCanadian Journal of Gastroenterology0835-79002003-01-0117211111310.1155/2003/768184Abdominal Pain as the Initial and Sole Clinical Presenting Feature of Systemic Lupus ErythematosusHenry V Chung0Alnoor Ramji1Jennifer E Davis2Sylvia Chang3Graham D Reid4Baljinder Salh5Hugh J Freeman6Eric M Yoshida7Department of Medicine, University of British Columbia, Vancouver, British Columbia, CanadaDepartment of Medicine, University of British Columbia, Vancouver, British Columbia, CanadaDepartment of Anatomic Pathology, University of British Columbia, Vancouver, British Columbia, CanadaDepartment of Radiology, University of British Columbia, Vancouver, British Columbia, CanadaDepartment of Medicine, University of British Columbia, Vancouver, British Columbia, CanadaDepartment of Medicine, University of British Columbia, Vancouver, British Columbia, CanadaDepartment of Medicine, University of British Columbia, Vancouver, British Columbia, CanadaDepartment of Medicine, University of British Columbia, Vancouver, British Columbia, CanadaClassically, a diagnosis of systemic lupus erythematosus (SLE) is dependent on renal, rheumatological, cutaneous and neurological target organ damage with supporting serological markers. A previously healthy 26-year-old Japanese woman whose only manifestation of otherwise occult SLE was severe abdominal pain is reported. A computed tomographic scan of the abdomen revealed thickened loops of small bowel, endoscopic findings were nonspecific and jejunal biopsy revealed a nonspecific enteritis. Laboratory studies revealed lymphopenia, hypocomplementemia, a positive antinuclear antibody, a weakly positive anti-Smith and a strongly positive anti-double stranded DNA. There was a prompt symptomatic recovery with immunosuppressive therapy. The authors’ experiences, and a review of the literature suggest that a diagnosis of SLE should be considered in young Asian women who present with significant but clinically enigmatic gastrointestinal illness.http://dx.doi.org/10.1155/2003/768184 |
| spellingShingle | Henry V Chung Alnoor Ramji Jennifer E Davis Sylvia Chang Graham D Reid Baljinder Salh Hugh J Freeman Eric M Yoshida Abdominal Pain as the Initial and Sole Clinical Presenting Feature of Systemic Lupus Erythematosus Canadian Journal of Gastroenterology |
| title | Abdominal Pain as the Initial and Sole Clinical Presenting Feature of Systemic Lupus Erythematosus |
| title_full | Abdominal Pain as the Initial and Sole Clinical Presenting Feature of Systemic Lupus Erythematosus |
| title_fullStr | Abdominal Pain as the Initial and Sole Clinical Presenting Feature of Systemic Lupus Erythematosus |
| title_full_unstemmed | Abdominal Pain as the Initial and Sole Clinical Presenting Feature of Systemic Lupus Erythematosus |
| title_short | Abdominal Pain as the Initial and Sole Clinical Presenting Feature of Systemic Lupus Erythematosus |
| title_sort | abdominal pain as the initial and sole clinical presenting feature of systemic lupus erythematosus |
| url | http://dx.doi.org/10.1155/2003/768184 |
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