Recent advances in the study of reproductive function in pediatric patients with brain tumors
In recent years, pediatric brain tumors have emerged as one of the most common malignant tumors among children. The site of tumor growth and the selected treatment modalities can potentially have a profound and significant impact on the reproductive function of pediatric patients, which is intimatel...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2025.1625359/full |
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| author | Rui Zhang Linlin Liu Xinyu Dai Yan Ju Yanming Ren |
| author_facet | Rui Zhang Linlin Liu Xinyu Dai Yan Ju Yanming Ren |
| author_sort | Rui Zhang |
| collection | DOAJ |
| description | In recent years, pediatric brain tumors have emerged as one of the most common malignant tumors among children. The site of tumor growth and the selected treatment modalities can potentially have a profound and significant impact on the reproductive function of pediatric patients, which is intimately associated with the physical and psychological health of children during their developmental process. Current research studies have demonstrated that pediatric patients diagnosed with germ cell tumors, craniopharyngiomas, and medulloblastomas commonly present with reproductive dysfunction. Regrettably, in clinical practice, neurosurgeons frequently fail to allocate sufficient attention to this particular aspect. It is of critical and urgent necessity to explore and elucidate the alterations in reproductive function among pediatric patients with brain tumors, and subsequently institute essential protective measures. This article is dedicated to comprehensively reviewing the latest research advancements regarding the relationship between pediatric brain tumors and reproductive function, thereby providing a valuable reference for safeguarding the reproductive function of pediatric patients afflicted with brain tumors. |
| format | Article |
| id | doaj-art-b613cec12bb9437ca719e50649bf7ee2 |
| institution | Kabale University |
| issn | 2296-2360 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj-art-b613cec12bb9437ca719e50649bf7ee22025-08-20T03:33:37ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602025-07-011310.3389/fped.2025.16253591625359Recent advances in the study of reproductive function in pediatric patients with brain tumorsRui Zhang0Linlin Liu1Xinyu Dai2Yan Ju3Yanming Ren4Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, ChinaThe First College of Clinical Medicine, Chongqing Medical University, Chongqing, ChinaDepartment of Anesthesiology, The First Affiliated Hospital, Chongqing Medical University, Chongqing, ChinaDepartment of Neurosurgery, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Neurosurgery, West China Hospital, Sichuan University, Chengdu, ChinaIn recent years, pediatric brain tumors have emerged as one of the most common malignant tumors among children. The site of tumor growth and the selected treatment modalities can potentially have a profound and significant impact on the reproductive function of pediatric patients, which is intimately associated with the physical and psychological health of children during their developmental process. Current research studies have demonstrated that pediatric patients diagnosed with germ cell tumors, craniopharyngiomas, and medulloblastomas commonly present with reproductive dysfunction. Regrettably, in clinical practice, neurosurgeons frequently fail to allocate sufficient attention to this particular aspect. It is of critical and urgent necessity to explore and elucidate the alterations in reproductive function among pediatric patients with brain tumors, and subsequently institute essential protective measures. This article is dedicated to comprehensively reviewing the latest research advancements regarding the relationship between pediatric brain tumors and reproductive function, thereby providing a valuable reference for safeguarding the reproductive function of pediatric patients afflicted with brain tumors.https://www.frontiersin.org/articles/10.3389/fped.2025.1625359/fullpediatricbrain tumorsneuroendocrinologyreproductive functionHPG axis |
| spellingShingle | Rui Zhang Linlin Liu Xinyu Dai Yan Ju Yanming Ren Recent advances in the study of reproductive function in pediatric patients with brain tumors Frontiers in Pediatrics pediatric brain tumors neuroendocrinology reproductive function HPG axis |
| title | Recent advances in the study of reproductive function in pediatric patients with brain tumors |
| title_full | Recent advances in the study of reproductive function in pediatric patients with brain tumors |
| title_fullStr | Recent advances in the study of reproductive function in pediatric patients with brain tumors |
| title_full_unstemmed | Recent advances in the study of reproductive function in pediatric patients with brain tumors |
| title_short | Recent advances in the study of reproductive function in pediatric patients with brain tumors |
| title_sort | recent advances in the study of reproductive function in pediatric patients with brain tumors |
| topic | pediatric brain tumors neuroendocrinology reproductive function HPG axis |
| url | https://www.frontiersin.org/articles/10.3389/fped.2025.1625359/full |
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