Moringa oleifera leaf extracts inhibit 6β-hydroxylation of testosterone by CYP3A4

Moringa oleifera leaf extracts inhibit 6β-hydroxylation of testosterone by CYP3A4

Background: Moringa oleifera is a tropical tree often used as a herbal medicine, including by people who test positive for HIV. Since herbal constituents may interact with drugs via inhibition of metabolizing enzymes, we investigated the effects of extracts of M. oleifera on the CYP3A4-mediated 6ß-h...

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Bibliographic Details
Main Authors: Tsitsi G. Monera, Alan R. Wolfe, Charles C. Maponga, Leslie Z. Benet, Joseph Guglielmo
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2008-10-01
Series:Journal of Infection in Developing Countries
Subjects:
Moringa oleifera
CYP3A4
herb-drug interaction
Online Access:https://jidc.org/index.php/journal/article/view/201
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