Atypical Distant Metastasis of Breast Malignant Phyllodes Tumors: A Case Report and Literature Review
Malignant phyllodes tumors (MPT) are rare breast neoplasms. Preoperative diagnosis is often challenging due to the unspecific clinical, radiological, and histological characteristics of the tumor. Dissemination pathways are local with chest wall invasion, regional with lymph nodes metastasis, and di...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Obstetrics and Gynecology |
| Online Access: | http://dx.doi.org/10.1155/2017/8963013 |
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| author | Tiphaine de Foucher Hélène Roussel Mikael Hivelin Léa Rossi Caroline Cornou Anne-Sophie Bats Myriam Deloménie Fabrice Lécuru Charlotte Ngô |
| author_facet | Tiphaine de Foucher Hélène Roussel Mikael Hivelin Léa Rossi Caroline Cornou Anne-Sophie Bats Myriam Deloménie Fabrice Lécuru Charlotte Ngô |
| author_sort | Tiphaine de Foucher |
| collection | DOAJ |
| description | Malignant phyllodes tumors (MPT) are rare breast neoplasms. Preoperative diagnosis is often challenging due to the unspecific clinical, radiological, and histological characteristics of the tumor. Dissemination pathways are local with chest wall invasion, regional with lymph nodes metastasis, and distant, hematogenous, mostly to the lungs, bones, and brain. Distant metastasis (DM) can be synchronous or appear months to years after the diagnosis and initial management. The current report describes the case of a 57-year-old woman presenting with a giant/neglected MPT of the breast, with no DM at initial staging, treated by radical modified mastectomy. Motor disorders due to medullar compression by a paravertebral mass appeared at short follow-up, also treated surgically. The patient died from several DM of rapid evolution. To our knowledge, this is the only case described of MPT with metastases to soft tissue causing medullar compression. We present a literature review on unusual metastatic localizations of MPT. |
| format | Article |
| id | doaj-art-b60f4d9b9c1b4bdaadf36f06c5ef0402 |
| institution | Kabale University |
| issn | 2090-6684 2090-6692 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Obstetrics and Gynecology |
| spelling | doaj-art-b60f4d9b9c1b4bdaadf36f06c5ef04022025-02-03T01:27:54ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922017-01-01201710.1155/2017/89630138963013Atypical Distant Metastasis of Breast Malignant Phyllodes Tumors: A Case Report and Literature ReviewTiphaine de Foucher0Hélène Roussel1Mikael Hivelin2Léa Rossi3Caroline Cornou4Anne-Sophie Bats5Myriam Deloménie6Fabrice Lécuru7Charlotte Ngô8Department of Breast and Gynecological Surgical Oncology, Hôpital Européen Georges Pompidou, AP-HP, Paris, FranceDepartment of Pathology, Hôpital Européen Georges Pompidou, AP-HP, Paris, FranceDepartment of Plastic and Reconstructive Surgery, Hôpital Européen Georges Pompidou, AP-HP, Paris, FranceDepartment of Breast and Gynecological Surgical Oncology, Hôpital Européen Georges Pompidou, AP-HP, Paris, FranceDepartment of Breast and Gynecological Surgical Oncology, Hôpital Européen Georges Pompidou, AP-HP, Paris, FranceDepartment of Breast and Gynecological Surgical Oncology, Hôpital Européen Georges Pompidou, AP-HP, Paris, FranceDepartment of Breast and Gynecological Surgical Oncology, Hôpital Européen Georges Pompidou, AP-HP, Paris, FranceDepartment of Breast and Gynecological Surgical Oncology, Hôpital Européen Georges Pompidou, AP-HP, Paris, FranceDepartment of Breast and Gynecological Surgical Oncology, Hôpital Européen Georges Pompidou, AP-HP, Paris, FranceMalignant phyllodes tumors (MPT) are rare breast neoplasms. Preoperative diagnosis is often challenging due to the unspecific clinical, radiological, and histological characteristics of the tumor. Dissemination pathways are local with chest wall invasion, regional with lymph nodes metastasis, and distant, hematogenous, mostly to the lungs, bones, and brain. Distant metastasis (DM) can be synchronous or appear months to years after the diagnosis and initial management. The current report describes the case of a 57-year-old woman presenting with a giant/neglected MPT of the breast, with no DM at initial staging, treated by radical modified mastectomy. Motor disorders due to medullar compression by a paravertebral mass appeared at short follow-up, also treated surgically. The patient died from several DM of rapid evolution. To our knowledge, this is the only case described of MPT with metastases to soft tissue causing medullar compression. We present a literature review on unusual metastatic localizations of MPT.http://dx.doi.org/10.1155/2017/8963013 |
| spellingShingle | Tiphaine de Foucher Hélène Roussel Mikael Hivelin Léa Rossi Caroline Cornou Anne-Sophie Bats Myriam Deloménie Fabrice Lécuru Charlotte Ngô Atypical Distant Metastasis of Breast Malignant Phyllodes Tumors: A Case Report and Literature Review Case Reports in Obstetrics and Gynecology |
| title | Atypical Distant Metastasis of Breast Malignant Phyllodes Tumors: A Case Report and Literature Review |
| title_full | Atypical Distant Metastasis of Breast Malignant Phyllodes Tumors: A Case Report and Literature Review |
| title_fullStr | Atypical Distant Metastasis of Breast Malignant Phyllodes Tumors: A Case Report and Literature Review |
| title_full_unstemmed | Atypical Distant Metastasis of Breast Malignant Phyllodes Tumors: A Case Report and Literature Review |
| title_short | Atypical Distant Metastasis of Breast Malignant Phyllodes Tumors: A Case Report and Literature Review |
| title_sort | atypical distant metastasis of breast malignant phyllodes tumors a case report and literature review |
| url | http://dx.doi.org/10.1155/2017/8963013 |
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