Diagnosis and treatment of pulmonary Aspergillus infection secondary to empyema complicated with lung cancer: a case report
BackgroundThis study aimed to explore the clinical characteristics, diagnosis, and management of Invasive Pulmonary Aspergillosis (IPA) complicating empyema in a patient with lung cancer.Case presentationWe analyzed the clinical manifestations, bronchoscopic findings, and therapeutic approaches, inc...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-08-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2025.1660190/full |
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| author | Chen Zhu Xiuli Liu Ying Gu Yuyao Shen Tingshu Jiang |
| author_facet | Chen Zhu Xiuli Liu Ying Gu Yuyao Shen Tingshu Jiang |
| author_sort | Chen Zhu |
| collection | DOAJ |
| description | BackgroundThis study aimed to explore the clinical characteristics, diagnosis, and management of Invasive Pulmonary Aspergillosis (IPA) complicating empyema in a patient with lung cancer.Case presentationWe analyzed the clinical manifestations, bronchoscopic findings, and therapeutic approaches, including anti-infective and anti-tumor treatments, in a patient diagnosed with IPA-associated empyema and lung cancer. Histopathological examination of bronchoscopic biopsy specimens confirmed pulmonary adenocarcinoma, while bronchoalveolar lavage fluid cultures identified Aspergillus fumigatus. Following the development of secondary empyema, comprehensive anti-infective and anti-tumor therapies were administered, leading to disease control. IPA-associated empyema complicating lung cancer represents a rare clinical scenario.ConclusionIn patients presenting with IPA, the potential coexistence of lung cancer should be considered. An integrated approach combining antifungal therapy and active anti-tumor treatment is essential for managing such cases. |
| format | Article |
| id | doaj-art-b60dd96a108642f38e732c408fac7cd0 |
| institution | Kabale University |
| issn | 2296-858X |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj-art-b60dd96a108642f38e732c408fac7cd02025-08-20T04:00:48ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-08-011210.3389/fmed.2025.16601901660190Diagnosis and treatment of pulmonary Aspergillus infection secondary to empyema complicated with lung cancer: a case reportChen ZhuXiuli LiuYing GuYuyao ShenTingshu JiangBackgroundThis study aimed to explore the clinical characteristics, diagnosis, and management of Invasive Pulmonary Aspergillosis (IPA) complicating empyema in a patient with lung cancer.Case presentationWe analyzed the clinical manifestations, bronchoscopic findings, and therapeutic approaches, including anti-infective and anti-tumor treatments, in a patient diagnosed with IPA-associated empyema and lung cancer. Histopathological examination of bronchoscopic biopsy specimens confirmed pulmonary adenocarcinoma, while bronchoalveolar lavage fluid cultures identified Aspergillus fumigatus. Following the development of secondary empyema, comprehensive anti-infective and anti-tumor therapies were administered, leading to disease control. IPA-associated empyema complicating lung cancer represents a rare clinical scenario.ConclusionIn patients presenting with IPA, the potential coexistence of lung cancer should be considered. An integrated approach combining antifungal therapy and active anti-tumor treatment is essential for managing such cases.https://www.frontiersin.org/articles/10.3389/fmed.2025.1660190/fulllung cancerempyemaBALFbronchoscopicInvasive Pulmonary Aspergillosis |
| spellingShingle | Chen Zhu Xiuli Liu Ying Gu Yuyao Shen Tingshu Jiang Diagnosis and treatment of pulmonary Aspergillus infection secondary to empyema complicated with lung cancer: a case report Frontiers in Medicine lung cancer empyema BALF bronchoscopic Invasive Pulmonary Aspergillosis |
| title | Diagnosis and treatment of pulmonary Aspergillus infection secondary to empyema complicated with lung cancer: a case report |
| title_full | Diagnosis and treatment of pulmonary Aspergillus infection secondary to empyema complicated with lung cancer: a case report |
| title_fullStr | Diagnosis and treatment of pulmonary Aspergillus infection secondary to empyema complicated with lung cancer: a case report |
| title_full_unstemmed | Diagnosis and treatment of pulmonary Aspergillus infection secondary to empyema complicated with lung cancer: a case report |
| title_short | Diagnosis and treatment of pulmonary Aspergillus infection secondary to empyema complicated with lung cancer: a case report |
| title_sort | diagnosis and treatment of pulmonary aspergillus infection secondary to empyema complicated with lung cancer a case report |
| topic | lung cancer empyema BALF bronchoscopic Invasive Pulmonary Aspergillosis |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2025.1660190/full |
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