Diagnosis and treatment of pulmonary Aspergillus infection secondary to empyema complicated with lung cancer: a case report
BackgroundThis study aimed to explore the clinical characteristics, diagnosis, and management of Invasive Pulmonary Aspergillosis (IPA) complicating empyema in a patient with lung cancer.Case presentationWe analyzed the clinical manifestations, bronchoscopic findings, and therapeutic approaches, inc...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-08-01
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| Series: | Frontiers in Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2025.1660190/full |
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| Summary: | BackgroundThis study aimed to explore the clinical characteristics, diagnosis, and management of Invasive Pulmonary Aspergillosis (IPA) complicating empyema in a patient with lung cancer.Case presentationWe analyzed the clinical manifestations, bronchoscopic findings, and therapeutic approaches, including anti-infective and anti-tumor treatments, in a patient diagnosed with IPA-associated empyema and lung cancer. Histopathological examination of bronchoscopic biopsy specimens confirmed pulmonary adenocarcinoma, while bronchoalveolar lavage fluid cultures identified Aspergillus fumigatus. Following the development of secondary empyema, comprehensive anti-infective and anti-tumor therapies were administered, leading to disease control. IPA-associated empyema complicating lung cancer represents a rare clinical scenario.ConclusionIn patients presenting with IPA, the potential coexistence of lung cancer should be considered. An integrated approach combining antifungal therapy and active anti-tumor treatment is essential for managing such cases. |
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| ISSN: | 2296-858X |