Global, regional, and national burden of cataract: A comprehensive analysis and projections from 1990 to 2021.
<h4>Objective</h4>Cataract is the most prevalent cause of blindness. Surgery remains the only effective and widely accepted treatment; early diagnosis and intervention can significantly prevent blindness. Hence,Understanding the current epidemiological status of cataract is crucial for f...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2025-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0326263 |
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| author | Lixia Lin Yongshun Liang Guiyang Jiang Qingqiao Gan Tianqi Yang Peipei Liao Hao Liang |
| author_facet | Lixia Lin Yongshun Liang Guiyang Jiang Qingqiao Gan Tianqi Yang Peipei Liao Hao Liang |
| author_sort | Lixia Lin |
| collection | DOAJ |
| description | <h4>Objective</h4>Cataract is the most prevalent cause of blindness. Surgery remains the only effective and widely accepted treatment; early diagnosis and intervention can significantly prevent blindness. Hence,Understanding the current epidemiological status of cataract is crucial for formulating better healthcare policies and effectively preventing blindness due to cataract.<h4>Design</h4>This study utilizes Global burden of Disease (GBD) 2021 data to conduct an in-depth analysis of the burden of cataract from 1990 to 2021, including gender disparities, risk factors, and the relationship between Socio-Demographic index (SDI) and disease burden. Additionally, we performed a frontier analysis of Disability-Adjusted Life Years (DALYs) due to cataract from 1990 to 2021. Finally, we used the BAPC model to project the burden of cataract by gender from 2022 to 2030.<h4>Results</h4>The study revealed that the global burden of cataract remains significant. Worldwide, the Estimate Annual Percentage Change (EAPC) for cataract prevalence was 0.2117([95% CI] 0.1172-0.3063); the EAPC for cataract DALYs is -0.4798([95%CI] -0.5766--0.3828). Predominantly affecting females, individuals aged 50 and older, and those in medium-low and low SDI regions. Furthermore, the Bayesian Age-Period-Cohort (BAPC) model forecast a gradual decline in the global burden of cataract over the next nine years.<h4>Conclusion</h4>This study utilized GBD 2021 to provide an in-depth analysis of the current global disease burden of cataracts. The results showed that although the Age-Standardized Rate (ASR) of DALYs decreased, the overall cataract Number still showed an increasing trend from 1990 to 2021 and 2022-2030. |
| format | Article |
| id | doaj-art-b60c0beb4461465ca0feefb579a86849 |
| institution | Kabale University |
| issn | 1932-6203 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-b60c0beb4461465ca0feefb579a868492025-08-20T03:32:15ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01206e032626310.1371/journal.pone.0326263Global, regional, and national burden of cataract: A comprehensive analysis and projections from 1990 to 2021.Lixia LinYongshun LiangGuiyang JiangQingqiao GanTianqi YangPeipei LiaoHao Liang<h4>Objective</h4>Cataract is the most prevalent cause of blindness. Surgery remains the only effective and widely accepted treatment; early diagnosis and intervention can significantly prevent blindness. Hence,Understanding the current epidemiological status of cataract is crucial for formulating better healthcare policies and effectively preventing blindness due to cataract.<h4>Design</h4>This study utilizes Global burden of Disease (GBD) 2021 data to conduct an in-depth analysis of the burden of cataract from 1990 to 2021, including gender disparities, risk factors, and the relationship between Socio-Demographic index (SDI) and disease burden. Additionally, we performed a frontier analysis of Disability-Adjusted Life Years (DALYs) due to cataract from 1990 to 2021. Finally, we used the BAPC model to project the burden of cataract by gender from 2022 to 2030.<h4>Results</h4>The study revealed that the global burden of cataract remains significant. Worldwide, the Estimate Annual Percentage Change (EAPC) for cataract prevalence was 0.2117([95% CI] 0.1172-0.3063); the EAPC for cataract DALYs is -0.4798([95%CI] -0.5766--0.3828). Predominantly affecting females, individuals aged 50 and older, and those in medium-low and low SDI regions. Furthermore, the Bayesian Age-Period-Cohort (BAPC) model forecast a gradual decline in the global burden of cataract over the next nine years.<h4>Conclusion</h4>This study utilized GBD 2021 to provide an in-depth analysis of the current global disease burden of cataracts. The results showed that although the Age-Standardized Rate (ASR) of DALYs decreased, the overall cataract Number still showed an increasing trend from 1990 to 2021 and 2022-2030.https://doi.org/10.1371/journal.pone.0326263 |
| spellingShingle | Lixia Lin Yongshun Liang Guiyang Jiang Qingqiao Gan Tianqi Yang Peipei Liao Hao Liang Global, regional, and national burden of cataract: A comprehensive analysis and projections from 1990 to 2021. PLoS ONE |
| title | Global, regional, and national burden of cataract: A comprehensive analysis and projections from 1990 to 2021. |
| title_full | Global, regional, and national burden of cataract: A comprehensive analysis and projections from 1990 to 2021. |
| title_fullStr | Global, regional, and national burden of cataract: A comprehensive analysis and projections from 1990 to 2021. |
| title_full_unstemmed | Global, regional, and national burden of cataract: A comprehensive analysis and projections from 1990 to 2021. |
| title_short | Global, regional, and national burden of cataract: A comprehensive analysis and projections from 1990 to 2021. |
| title_sort | global regional and national burden of cataract a comprehensive analysis and projections from 1990 to 2021 |
| url | https://doi.org/10.1371/journal.pone.0326263 |
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