Feasibility of magnetic resonance imaging-guided cardiac catheterization, angioplasty, and stenting in a commercial wide-bore 0.55T scanner
ABSTRACT: Background: Low-field (0.55T) magnetic resonance imaging (MRI) may allow MRI-guided interventions using available catheterization equipment, as radiofrequency-induced heating of interventional devices is reduced at low field. The purpose of this study was to test the feasibility of real-t...
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Elsevier
2025-01-01
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| Series: | Journal of Cardiovascular Magnetic Resonance |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1097664725000201 |
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| author | Aimee K. Armstrong Yixuan Liu John M. Kelly Ramkumar Krishnamurthy Jason Swinning Yingmin Liu Matthew Joseph Ning Jin Jianing Pang Florian Maier Axel J. Krafft Orville Bramwell Nathan Ooms Jesse Roll Joshua Krieger David C. Gross Lucien de Mos Paul Borm Orlando P. Simonetti |
| author_facet | Aimee K. Armstrong Yixuan Liu John M. Kelly Ramkumar Krishnamurthy Jason Swinning Yingmin Liu Matthew Joseph Ning Jin Jianing Pang Florian Maier Axel J. Krafft Orville Bramwell Nathan Ooms Jesse Roll Joshua Krieger David C. Gross Lucien de Mos Paul Borm Orlando P. Simonetti |
| author_sort | Aimee K. Armstrong |
| collection | DOAJ |
| description | ABSTRACT: Background: Low-field (0.55T) magnetic resonance imaging (MRI) may allow MRI-guided interventions using available catheterization equipment, as radiofrequency-induced heating of interventional devices is reduced at low field. The purpose of this study was to test the feasibility of real-time MRI-guided right and left heart catheterization (R&LHC) as well as angioplasty and stenting of the inferior vena cava using a commercially available 0.55T MRI system (MAGNETOM Free.Max, Siemens Healthineers AG, Erlangen, Germany) with 80 cm patient bore and maximum gradient amplitude and slew rate of 26 mT/m and 45 mT/m/ms, respectively. A secondary aim was to evaluate three different sizes of magnetic resonance (MR)-visible markers. Methods: Sheaths were placed in the femoral vein and artery of juvenile Yorkshire pigs under general anesthesia. Air-filled balloon wedge catheters and Judkins right catheters were used for R&LHC, respectively, aided by an MR-compatible guidewire. Ferumoxytol was administered as a T1-shortening contrast agent and real-time visualization was carried out with a research interactive sequence using different spatiotemporal resolution settings. IVC angioplasty was performed using balloons filled with 1% gadolinium, and IVC stenting was performed with stainless-steel stents and one platinum-iridium-covered sten. Results: RHC was successful in all eight attempts with balloon tip visibility in all real-time protocols. One pig expired with ferumoxytol infusion, but the catheterization was completed post-mortem. LHC and IVC angioplasty were attempted and successful in two and four pigs, respectively. For stenting, higher resolution, lower frame rate imaging was used. All six attempted stent implantations were successful. The MR markers on the angioplasty balloon with widths of 0.5 and 1 mm were more visible than the 0.25 mm markers. Marker placement affected distinguishability from the crimped stent. Stainless-steel stents created only minimal signal voids pre- and post-deployment; however, the platinum-iridium stent caused significant artifact obscuring wall apposition assessment. Conclusion: This study is the first to demonstrate the technical feasibility of R&LHC, IVC angioplasty, and IVC stenting using real-time MRI on a commercially available low-field scanner. |
| format | Article |
| id | doaj-art-b60a72b3fcb440429fd6aee856619a3d |
| institution | OA Journals |
| issn | 1097-6647 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
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| series | Journal of Cardiovascular Magnetic Resonance |
| spelling | doaj-art-b60a72b3fcb440429fd6aee856619a3d2025-08-20T02:34:15ZengElsevierJournal of Cardiovascular Magnetic Resonance1097-66472025-01-0127110185810.1016/j.jocmr.2025.101858Feasibility of magnetic resonance imaging-guided cardiac catheterization, angioplasty, and stenting in a commercial wide-bore 0.55T scannerAimee K. Armstrong0Yixuan Liu1John M. Kelly2Ramkumar Krishnamurthy3Jason Swinning4Yingmin Liu5Matthew Joseph6Ning Jin7Jianing Pang8Florian Maier9Axel J. Krafft10Orville Bramwell11Nathan Ooms12Jesse Roll13Joshua Krieger14David C. Gross15Lucien de Mos16Paul Borm17Orlando P. Simonetti18The Heart Center, Nationwide Children’s Hospital, Columbus, Ohio, USA; Department of Pediatrics, The Ohio State University, Columbus, Ohio, USADepartment of Biomedical Engineering, The Ohio State University, Columbus, Ohio, USAThe Heart Center, Nationwide Children’s Hospital, Columbus, Ohio, USA; Department of Pediatrics, The Ohio State University, Columbus, Ohio, USAMedical and Scientific Affairs, Icon Clinical Research, Blue Bell, Pennsylvania, USAThe Heart Center, Nationwide Children’s Hospital, Columbus, Ohio, USADorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio, USADorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio, USASiemens Medical Solutions USA Inc., Malvern, Pennsylvania, USASiemens Medical Solutions USA Inc., Malvern, Pennsylvania, USASiemens Healthineers AG, Erlangen,GermanySiemens Healthineers AG, Erlangen,GermanyCook Advanced Technologies, West Lafayette, Indiana, USACook Advanced Technologies, West Lafayette, Indiana, USACook Advanced Technologies, West Lafayette, Indiana, USACook Advanced Technologies, West Lafayette, Indiana, USAMED Institute, West Lafayette, Indiana, USANano4Imaging GmbH, Life Sciences Centre, Düsseldorf, GermanyNano4Imaging GmbH, Life Sciences Centre, Düsseldorf, GermanyDepartment of Radiology, The Ohio State University, Columbus, Ohio, USA; Division of Cardiovascular Medicine, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, USA; Corresponding author.ABSTRACT: Background: Low-field (0.55T) magnetic resonance imaging (MRI) may allow MRI-guided interventions using available catheterization equipment, as radiofrequency-induced heating of interventional devices is reduced at low field. The purpose of this study was to test the feasibility of real-time MRI-guided right and left heart catheterization (R&LHC) as well as angioplasty and stenting of the inferior vena cava using a commercially available 0.55T MRI system (MAGNETOM Free.Max, Siemens Healthineers AG, Erlangen, Germany) with 80 cm patient bore and maximum gradient amplitude and slew rate of 26 mT/m and 45 mT/m/ms, respectively. A secondary aim was to evaluate three different sizes of magnetic resonance (MR)-visible markers. Methods: Sheaths were placed in the femoral vein and artery of juvenile Yorkshire pigs under general anesthesia. Air-filled balloon wedge catheters and Judkins right catheters were used for R&LHC, respectively, aided by an MR-compatible guidewire. Ferumoxytol was administered as a T1-shortening contrast agent and real-time visualization was carried out with a research interactive sequence using different spatiotemporal resolution settings. IVC angioplasty was performed using balloons filled with 1% gadolinium, and IVC stenting was performed with stainless-steel stents and one platinum-iridium-covered sten. Results: RHC was successful in all eight attempts with balloon tip visibility in all real-time protocols. One pig expired with ferumoxytol infusion, but the catheterization was completed post-mortem. LHC and IVC angioplasty were attempted and successful in two and four pigs, respectively. For stenting, higher resolution, lower frame rate imaging was used. All six attempted stent implantations were successful. The MR markers on the angioplasty balloon with widths of 0.5 and 1 mm were more visible than the 0.25 mm markers. Marker placement affected distinguishability from the crimped stent. Stainless-steel stents created only minimal signal voids pre- and post-deployment; however, the platinum-iridium stent caused significant artifact obscuring wall apposition assessment. Conclusion: This study is the first to demonstrate the technical feasibility of R&LHC, IVC angioplasty, and IVC stenting using real-time MRI on a commercially available low-field scanner.http://www.sciencedirect.com/science/article/pii/S1097664725000201Interventional cardiovascular magnetic resonance imagingLow-field MRIMRI-guided procedures |
| spellingShingle | Aimee K. Armstrong Yixuan Liu John M. Kelly Ramkumar Krishnamurthy Jason Swinning Yingmin Liu Matthew Joseph Ning Jin Jianing Pang Florian Maier Axel J. Krafft Orville Bramwell Nathan Ooms Jesse Roll Joshua Krieger David C. Gross Lucien de Mos Paul Borm Orlando P. Simonetti Feasibility of magnetic resonance imaging-guided cardiac catheterization, angioplasty, and stenting in a commercial wide-bore 0.55T scanner Journal of Cardiovascular Magnetic Resonance Interventional cardiovascular magnetic resonance imaging Low-field MRI MRI-guided procedures |
| title | Feasibility of magnetic resonance imaging-guided cardiac catheterization, angioplasty, and stenting in a commercial wide-bore 0.55T scanner |
| title_full | Feasibility of magnetic resonance imaging-guided cardiac catheterization, angioplasty, and stenting in a commercial wide-bore 0.55T scanner |
| title_fullStr | Feasibility of magnetic resonance imaging-guided cardiac catheterization, angioplasty, and stenting in a commercial wide-bore 0.55T scanner |
| title_full_unstemmed | Feasibility of magnetic resonance imaging-guided cardiac catheterization, angioplasty, and stenting in a commercial wide-bore 0.55T scanner |
| title_short | Feasibility of magnetic resonance imaging-guided cardiac catheterization, angioplasty, and stenting in a commercial wide-bore 0.55T scanner |
| title_sort | feasibility of magnetic resonance imaging guided cardiac catheterization angioplasty and stenting in a commercial wide bore 0 55t scanner |
| topic | Interventional cardiovascular magnetic resonance imaging Low-field MRI MRI-guided procedures |
| url | http://www.sciencedirect.com/science/article/pii/S1097664725000201 |
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