Spontaneous Formation of Solid Shell Polymeric Multicompartments at All‐Aqueous Interfaces
Abstract Multicompartmental capsules have demonstrated value in fields ranging from drug release, mimetics of artificial cells, to energy conversion and storage. However, the fabrication of devices with different compartments usually requires the use of toxic solvents, and/or the adaptation of techn...
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| Format: | Article |
| Language: | English |
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Wiley
2024-12-01
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| Series: | Advanced Science |
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| Online Access: | https://doi.org/10.1002/advs.202402592 |
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| author | Francisca G. Perfeito Sara Vilabril Andreia Cerqueira Mariana B. Oliveira João F. Mano |
| author_facet | Francisca G. Perfeito Sara Vilabril Andreia Cerqueira Mariana B. Oliveira João F. Mano |
| author_sort | Francisca G. Perfeito |
| collection | DOAJ |
| description | Abstract Multicompartmental capsules have demonstrated value in fields ranging from drug release, mimetics of artificial cells, to energy conversion and storage. However, the fabrication of devices with different compartments usually requires the use of toxic solvents, and/or the adaptation of technically demanding methods, including precision microfluidics and multistep processes. The spontaneous formation of multi‐core capsules resulting from polyelectrolyte complexation at the interface of a prototypic all‐aqueous two‐phase system is described here. The variation of polyelectrolyte concentration and complexation time are described as simple working parameters capable of driving the formation of compartments at different yields, as well as tailoring their morphology. The mild processing technology enables the encapsulation of animal cells, which are capable of invading capsule walls for specific processing conditions. |
| format | Article |
| id | doaj-art-b604e717c2aa461e824e9e983143dbbf |
| institution | Kabale University |
| issn | 2198-3844 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advanced Science |
| spelling | doaj-art-b604e717c2aa461e824e9e983143dbbf2024-12-04T12:14:54ZengWileyAdvanced Science2198-38442024-12-011145n/an/a10.1002/advs.202402592Spontaneous Formation of Solid Shell Polymeric Multicompartments at All‐Aqueous InterfacesFrancisca G. Perfeito0Sara Vilabril1Andreia Cerqueira2Mariana B. Oliveira3João F. Mano4Department of Chemistry CICECO – Aveiro Institute of Materials University of Aveiro Aveiro 3810‐193 PortugalDepartment of Chemistry CICECO – Aveiro Institute of Materials University of Aveiro Aveiro 3810‐193 PortugalDepartment of Chemistry CICECO – Aveiro Institute of Materials University of Aveiro Aveiro 3810‐193 PortugalDepartment of Chemistry CICECO – Aveiro Institute of Materials University of Aveiro Aveiro 3810‐193 PortugalDepartment of Chemistry CICECO – Aveiro Institute of Materials University of Aveiro Aveiro 3810‐193 PortugalAbstract Multicompartmental capsules have demonstrated value in fields ranging from drug release, mimetics of artificial cells, to energy conversion and storage. However, the fabrication of devices with different compartments usually requires the use of toxic solvents, and/or the adaptation of technically demanding methods, including precision microfluidics and multistep processes. The spontaneous formation of multi‐core capsules resulting from polyelectrolyte complexation at the interface of a prototypic all‐aqueous two‐phase system is described here. The variation of polyelectrolyte concentration and complexation time are described as simple working parameters capable of driving the formation of compartments at different yields, as well as tailoring their morphology. The mild processing technology enables the encapsulation of animal cells, which are capable of invading capsule walls for specific processing conditions.https://doi.org/10.1002/advs.202402592capsulesinterfacial complexationmulticompartmentspolyelectrolytessoft materials |
| spellingShingle | Francisca G. Perfeito Sara Vilabril Andreia Cerqueira Mariana B. Oliveira João F. Mano Spontaneous Formation of Solid Shell Polymeric Multicompartments at All‐Aqueous Interfaces Advanced Science capsules interfacial complexation multicompartments polyelectrolytes soft materials |
| title | Spontaneous Formation of Solid Shell Polymeric Multicompartments at All‐Aqueous Interfaces |
| title_full | Spontaneous Formation of Solid Shell Polymeric Multicompartments at All‐Aqueous Interfaces |
| title_fullStr | Spontaneous Formation of Solid Shell Polymeric Multicompartments at All‐Aqueous Interfaces |
| title_full_unstemmed | Spontaneous Formation of Solid Shell Polymeric Multicompartments at All‐Aqueous Interfaces |
| title_short | Spontaneous Formation of Solid Shell Polymeric Multicompartments at All‐Aqueous Interfaces |
| title_sort | spontaneous formation of solid shell polymeric multicompartments at all aqueous interfaces |
| topic | capsules interfacial complexation multicompartments polyelectrolytes soft materials |
| url | https://doi.org/10.1002/advs.202402592 |
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