Heart rate variability in female soccer players, before, during, and after a COVID-19 positive test

Abstract The purpose of this study is to examine the impact of COVID-19 infection on heart rate variability (HRV) in female soccer players, with a focus on identifying changes in autonomic regulation before, during, and after a COVID-19 positive test. Seven elite female soccer players (age: 20.14 ± ...

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Main Authors: Koulla Parpa, Ana C. Paludo, Karuppasamy Govindasamy, Georgian Badicu, Marcos Michaelides
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-10747-y
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Summary:Abstract The purpose of this study is to examine the impact of COVID-19 infection on heart rate variability (HRV) in female soccer players, with a focus on identifying changes in autonomic regulation before, during, and after a COVID-19 positive test. Seven elite female soccer players (age: 20.14 ± 6.41 years, height: 162.43 ± 4.32 cm, weight: 51.73 ± 5.65 kg) were included in the analysis after consistently recording their HRV during the specified period. Morning HRV measures were completed using photoplethysmography via the HRV4 training smartphone application, a validated tool for field-based monitoring, along with self-reported data. The players were tracked for at least 30 consecutive days before testing positive for COVID-19 using a polymerase chain reaction (PCR) test. They were also requested to record their HRV while they had COVID-19 until a negative PCR result was obtained. The study presents data on RMSSD, LnRMSSD and HR for the 30 days prior to COVID-19, as well as for the 3 days (day − 3), 2 days (day − 2), and 1 day (day − 1) leading up to COVID-19. Also, data for the first 5 days following a positive COVID-19 test are included. The results of this study indicated that LnRMSSD measurements were significantly lower 2 days (day − 2) and 1 day (day − 1) before the onset of COVID-19, as well as during the first four days following a positive COVID-19 test, compared to baseline. In addition, RMSSD measurements were significantly lower during the first 4 days after a positive COVID-19 test, while resting heart rate was significantly higher during the first and second days following a positive COVID-19 test, compared to baseline. Our findings suggest that reductions in LnRMSSD, reflecting decreased parasympathetic activity, may serve as early indicators of COVID-19 infection in elite female soccer players, potentially allowing for pre-symptomatic detection through daily HRV monitoring.
ISSN:2045-2322