Mixed Germ Cell Testicular Cancer with Left Ventricular Metastasis Presenting with Embolic Stroke and Small Bowel Tumor Seeding

Testicular germ cell tumors (GCTs) metastasize in a very predictable fashion involving the retroperitoneal nodes first followed by hematogenous spread to distant organs like lungs, liver, and brain. Metastasis to heart is an extremely rare entity for GCT and fewer than 20 cases have been reported in...

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Main Authors: Srinath Sundararajan, Beth Braunhut, Frederick Ahmann, Amit Agarwal
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2014/250531
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author Srinath Sundararajan
Beth Braunhut
Frederick Ahmann
Amit Agarwal
author_facet Srinath Sundararajan
Beth Braunhut
Frederick Ahmann
Amit Agarwal
author_sort Srinath Sundararajan
collection DOAJ
description Testicular germ cell tumors (GCTs) metastasize in a very predictable fashion involving the retroperitoneal nodes first followed by hematogenous spread to distant organs like lungs, liver, and brain. Metastasis to heart is an extremely rare entity for GCT and fewer than 20 cases have been reported in the literature so far. We have summarized here a unique case of nonseminomatous germ cell tumor (NSGCT) with intracardiac metastasis resulting in systemic macroembolization to liver, spleen, brain, bowel and musculoskeletal tissues. This led to multiple adverse sequelae including ischemic stroke and bowel perforation.
format Article
id doaj-art-b5f7506095524c8cbf1e290c6a1f85ed
institution Kabale University
issn 2090-6706
2090-6714
language English
publishDate 2014-01-01
publisher Wiley
record_format Article
series Case Reports in Oncological Medicine
spelling doaj-art-b5f7506095524c8cbf1e290c6a1f85ed2025-02-03T06:42:04ZengWileyCase Reports in Oncological Medicine2090-67062090-67142014-01-01201410.1155/2014/250531250531Mixed Germ Cell Testicular Cancer with Left Ventricular Metastasis Presenting with Embolic Stroke and Small Bowel Tumor SeedingSrinath Sundararajan0Beth Braunhut1Frederick Ahmann2Amit Agarwal3Department of Hematology-Oncology, University of Arizona, Tucson, AZ 85724, USADepartment of Pathology, University of Arizona, Tucson, AZ 85724, USADepartment of Hematology-Oncology, University of Arizona, Tucson, AZ 85724, USADepartment of Hematology-Oncology, University of Arizona, Tucson, AZ 85724, USATesticular germ cell tumors (GCTs) metastasize in a very predictable fashion involving the retroperitoneal nodes first followed by hematogenous spread to distant organs like lungs, liver, and brain. Metastasis to heart is an extremely rare entity for GCT and fewer than 20 cases have been reported in the literature so far. We have summarized here a unique case of nonseminomatous germ cell tumor (NSGCT) with intracardiac metastasis resulting in systemic macroembolization to liver, spleen, brain, bowel and musculoskeletal tissues. This led to multiple adverse sequelae including ischemic stroke and bowel perforation.http://dx.doi.org/10.1155/2014/250531
spellingShingle Srinath Sundararajan
Beth Braunhut
Frederick Ahmann
Amit Agarwal
Mixed Germ Cell Testicular Cancer with Left Ventricular Metastasis Presenting with Embolic Stroke and Small Bowel Tumor Seeding
Case Reports in Oncological Medicine
title Mixed Germ Cell Testicular Cancer with Left Ventricular Metastasis Presenting with Embolic Stroke and Small Bowel Tumor Seeding
title_full Mixed Germ Cell Testicular Cancer with Left Ventricular Metastasis Presenting with Embolic Stroke and Small Bowel Tumor Seeding
title_fullStr Mixed Germ Cell Testicular Cancer with Left Ventricular Metastasis Presenting with Embolic Stroke and Small Bowel Tumor Seeding
title_full_unstemmed Mixed Germ Cell Testicular Cancer with Left Ventricular Metastasis Presenting with Embolic Stroke and Small Bowel Tumor Seeding
title_short Mixed Germ Cell Testicular Cancer with Left Ventricular Metastasis Presenting with Embolic Stroke and Small Bowel Tumor Seeding
title_sort mixed germ cell testicular cancer with left ventricular metastasis presenting with embolic stroke and small bowel tumor seeding
url http://dx.doi.org/10.1155/2014/250531
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AT frederickahmann mixedgermcelltesticularcancerwithleftventricularmetastasispresentingwithembolicstrokeandsmallboweltumorseeding
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