CYTOPROTECTOR ROLE IN THE MANAGEMENT OF ARTERIAL HYPERTENSION TREATED WITH ENALAPRIL
The study investigated the effects of cardiac cytoprotectors – mildronate and trimetazidine, combined with ACE therapy, on lipid peroxidation product levels, endothelial function, circadian blood pressure (BP) profile, left ventricular myocardium, and intracardiac hemodynamics in patients with arter...
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| Format: | Article |
| Language: | Russian |
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«FIRMA «SILICEA» LLC
2009-10-01
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| Series: | Российский кардиологический журнал |
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| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/1386 |
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| _version_ | 1850026992422879232 |
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| author | F. E. Khebodarov V. P. Mikhin |
| author_facet | F. E. Khebodarov V. P. Mikhin |
| author_sort | F. E. Khebodarov |
| collection | DOAJ |
| description | The study investigated the effects of cardiac cytoprotectors – mildronate and trimetazidine, combined with ACE therapy, on lipid peroxidation product levels, endothelial function, circadian blood pressure (BP) profile, left ventricular myocardium, and intracardiac hemodynamics in patients with arterial hypertension (AH). It was demonstrated that in AH patients, the combination of mildronate and enalapril facilitated lipid peroxidation reduction, endothelial function and circadian BP normalization, as well as improvement of left ventricular morphology and function. The combination of trimetazidine and enalapril did not improve the effectiveness of antihypertensive therapy. |
| format | Article |
| id | doaj-art-b5e9ed0e050c4d718d567946dc7b6df6 |
| institution | DOAJ |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| publishDate | 2009-10-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj-art-b5e9ed0e050c4d718d567946dc7b6df62025-08-20T03:00:22Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202009-10-010546501175CYTOPROTECTOR ROLE IN THE MANAGEMENT OF ARTERIAL HYPERTENSION TREATED WITH ENALAPRILF. E. Khebodarov0V. P. Mikhin1ФГУЗ – Медсанчасть УВД по Курской области, КурскКурский государственный медицинский университет, кафедра внутренних болезней № 2The study investigated the effects of cardiac cytoprotectors – mildronate and trimetazidine, combined with ACE therapy, on lipid peroxidation product levels, endothelial function, circadian blood pressure (BP) profile, left ventricular myocardium, and intracardiac hemodynamics in patients with arterial hypertension (AH). It was demonstrated that in AH patients, the combination of mildronate and enalapril facilitated lipid peroxidation reduction, endothelial function and circadian BP normalization, as well as improvement of left ventricular morphology and function. The combination of trimetazidine and enalapril did not improve the effectiveness of antihypertensive therapy.https://russjcardiol.elpub.ru/jour/article/view/1386arterial hypertensioncardiac cytoprotectorsenalapril |
| spellingShingle | F. E. Khebodarov V. P. Mikhin CYTOPROTECTOR ROLE IN THE MANAGEMENT OF ARTERIAL HYPERTENSION TREATED WITH ENALAPRIL Российский кардиологический журнал arterial hypertension cardiac cytoprotectors enalapril |
| title | CYTOPROTECTOR ROLE IN THE MANAGEMENT OF ARTERIAL HYPERTENSION TREATED WITH ENALAPRIL |
| title_full | CYTOPROTECTOR ROLE IN THE MANAGEMENT OF ARTERIAL HYPERTENSION TREATED WITH ENALAPRIL |
| title_fullStr | CYTOPROTECTOR ROLE IN THE MANAGEMENT OF ARTERIAL HYPERTENSION TREATED WITH ENALAPRIL |
| title_full_unstemmed | CYTOPROTECTOR ROLE IN THE MANAGEMENT OF ARTERIAL HYPERTENSION TREATED WITH ENALAPRIL |
| title_short | CYTOPROTECTOR ROLE IN THE MANAGEMENT OF ARTERIAL HYPERTENSION TREATED WITH ENALAPRIL |
| title_sort | cytoprotector role in the management of arterial hypertension treated with enalapril |
| topic | arterial hypertension cardiac cytoprotectors enalapril |
| url | https://russjcardiol.elpub.ru/jour/article/view/1386 |
| work_keys_str_mv | AT fekhebodarov cytoprotectorroleinthemanagementofarterialhypertensiontreatedwithenalapril AT vpmikhin cytoprotectorroleinthemanagementofarterialhypertensiontreatedwithenalapril |